ReviewCancer genomics & proteomics
The spectra count label-free quantitation in cancer proteomics.
Review in Cancer genomics & proteomics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.Nature communications · 2019Pooled it
- Area under the curve quantification outperforms spectral counting in metaproteomics, but matching between runs is detrimental.bioRxiv : the preprint server for biology · 2026Article
- Neurogranin-MYH9 interaction regulates cytoskeletal remodeling in cerebral vasculature.Fluids and barriers of the CNS · 2025Article
- Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol.Journal of neuroendocrinology · 2025Article
- High-quality and robust protein quantification in large clinical/pharmaceutical cohorts with IonStar proteomics investigation.Nature protocols · 2023Review
- Recent advances in mass spectrometry analysis of neuropeptides.Mass spectrometry reviews · 2023Review
- Mining Unknown Porcine Protein Isoforms by Tissue-based Map of Proteome Enhances Pig Genome Annotation.Genomics, proteomics & bioinformatics · 2021Article
- Proteomic Interrogation in Cancer Biomarker.Advances in experimental medicine and biology · 2021Article
- An Integrated Workflow for Global, Glyco-, and Phospho-proteomic Analysis of Tumor Tissues.Analytical chemistry · 2020Article
- MS1 ion current-based quantitative proteomics: A promising solution for reliable analysis of large biological cohorts.Mass spectrometry reviews · 2019Review
- Quantification of species-specific meat proteins in cooked and smoked sausages using infusion mass spectrometry.Journal of food science and technology · 2018Article
- HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.Nature communications · 2018Article
- LC-MS/MS Analysis Unravels Deep Oxidation of Manganese Superoxide Dismutase in Kidney Cancer.International journal of molecular sciences · 2017Article
- Efficient Microscale Basic Reverse Phase Peptide Fractionation for Global and Targeted Proteomics.Journal of proteome research · 2016Article
- MetaPro-IQ: a universal metaproteomic approach to studying human and mouse gut microbiota.Microbiome · 2016Article
- Capturing and identification of differentially expressed fucome by a gel free and label free approach.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2015Article
- Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity.Nature communications · 2015Article
- Application of clinical proteomics in acute respiratory distress syndrome.Clinical and translational medicine · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Mass spectrometry is used routinely for large-scale protein identification from complex biological mixtures. Recently, relative quantitation approach on the basis of spectra count has been applied in several cancer proteomic studies. In this review, we examine the mechanism of this technique and highlight several important parameters associated with its application.
Indexed as
Identifiers
22593248PMC3761408What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.