Evidence map›Paper›PMID 22592899›Full record

ArticleCirculation2012

Targeting endoglin, an auxiliary transforming growth factor β coreceptor, to prevent fibrosis and heart failure.

Ivor J Benjamin

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. The Role of Endoglin in Myocardial Fibrosis.Acta Cardiologica Sinica · 2017
    Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Ivor J Benjamin

Funding

Protein Misfolding Diseases and Oxido-Reductive PathwaysDP1OD006438 · OD · UNIVERSITY OF UTAH · PI BENJAMIN, IVOR JAMES · 2009 to 2011
$2.2M
Reductive Stress in the Pathogenesis of R120GCryAB CardiomyopathyR01HL063834 · NHLBI · UNIVERSITY OF UTAH · PI BENJAMIN, IVOR JAMES · 2000 to 2010
$2.2M
Mechanisms of HSPB2 in Cardiac Metabolism and Ischemic CardioprotectionR01HL074370 · NHLBI · UNIVERSITY OF UTAH · PI BENJAMIN, IVOR JAMES · 2008 to 2011
$1.5M
Protein Misfolding Diseases and Oxido-Reductive PathwaysDP1HL117650 · NHLBI · UNIVERSITY OF UTAH · PI BENJAMIN, IVOR JAMES · 2012 to 2013
$1.5M
NHLBI NIH HHS 2 R01 HL063834-06NHLBI NIH HHS 5R01HL074370-03NHLBI NIH HHS DP1 HL117650NHLBI NIH HHS R01 HL063834NHLBI NIH HHS R01 HL074370NIH HHS DP1 OD006438
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntigens, CDEndoglinHeart FailureHumansIntracellular Signaling Peptides and ProteinsMaleMyocardiumReceptors, Cell SurfaceAntigens, CDEndoglinENG protein, humanEng protein, mouseIntracellular Signaling Peptides and ProteinsReceptors, Cell Surface

Identifiers

PMID22592899
PMCPMC3401168

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.