ArticleSexually transmitted diseases2012
Exploring the potential impact of a reduction in partnership concurrency on HIV incidence in rural Uganda: a modeling study.
Article in Sexually transmitted diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Review of Network Models for HIV Spread.Journal of acquired immune deficiency syndromes (1999) · 2025Pooled it
- Modelling HIV/AIDS epidemiological complexity: A scoping review of Agent-Based Models and their application.PloS one · 2024Article
- The use of mixture density networks in the emulation of complex epidemiological individual-based models.PLoS computational biology · 2020Article
- The differential impacts of non-locally acquired infections and treatment interventions on heterosexual HIV transmission in Hong Kong.PloS one · 2020Article
- Effect of HPV vaccination and cervical cancer screening in England by ethnicity: a modelling study.The Lancet. Public health · 2018Article
- Choice of time horizon critical in estimating costs and effects of changes to HIV programmes.PloS one · 2018Article
- Improving ART programme retention and viral suppression are key to maximising impact of treatment as prevention - a modelling study.BMC infectious diseases · 2017Article
- History matching of a complex epidemiological model of human immunodeficiency virus transmission by using variance emulation.Journal of the Royal Statistical Society. Series C, Applied statistics · 2017Article
- Universal test, treat, and keep: improving ART retention is key in cost-effective HIV control in Uganda.BMC infectious diseases · 2017Article
- Effectiveness of combination packages for HIV-1 prevention in sub-Saharan Africa depends on partnership network structure: a mathematical modelling study.Sexually transmitted infections · 2016Article
- Attitudes Towards Power in Relationships and Sexual Concurrency Within Heterosexual Youth Partnerships in Baltimore, MD.AIDS and behavior · 2015Article
- Bayesian history matching of complex infectious disease models using emulation: a tutorial and a case study on HIV in Uganda.PLoS computational biology · 2015Article
- Article
- Measuring and modelling concurrency.Journal of the International AIDS Society · 2013Review
- Individual-based simulation models of HIV transmission: reporting quality and recommendations.PloS one · 2013Review
- Put in context: the concurrency intervention simulation study of McCreesh et al.Sexually transmitted diseases · 2012Article
- What impact will reducing concurrency have on decreasing the incidence of HIV in heterosexual populations?Sexually transmitted diseases · 2012Article
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8 authors.
Funding
Abstract
backgroundA number of African countries have planned campaigns against concurrency. It will not be possible to separate the effects of a reduction in concurrency from other behavior changes when evaluating these campaigns. This modeling study explores the potential impact of an intervention to reduce partnership concurrency on HIV incidence in contemporary rural Uganda, keeping incidence of sex acts and partnerships in the population constant.
methodsData on demography, sexual behavior, and HIV prevalence from Uganda were used to parameterize an individual-based HIV transmission model. Three baseline model scenarios were simulated, representing the best estimate of concurrency prevalence in this population, and low and high plausible bounds. Interventions that reduced concurrency by 20% and 50% between 2010 and 2020 were simulated, and the impact on HIV incidence in 2020 was calculated.
resultsData showed 9.6% (7.9%-11.4%) of men and 0.2% (0.0%-0.4%) of women reported concurrency in 2008. Reducing concurrency had a nonlinear impact on HIV incidence. A 20% reduction in concurrency reduced HIV incidence by 4.1% (0.3%-5.7%) in men and 9.2% (2.1%-16.8%) in women; a 50% reduction in concurrency reduced HIV incidence by 6.0% (1.4%-10.8%) in men and 16.2% (6.3%-23.4%) in women.
conclusionsInterventions against concurrency have the potential to reduce HIV incidence and may have a higher impact in women than in men. In rural Uganda, overall impact was modest, and this study does not provide strong support for the prioritization of concurrency as a target for behavior change interventions. However, it may be more useful in higher concurrency settings and for reducing HIV incidence in women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.