SynthesisThe Cochrane database of systematic reviews2012
Spiritual and religious interventions for well-being of adults in the terminal phase of disease.
Synthesis in The Cochrane database of systematic reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Barriers and enablers of implementing spiritual care at the end of life: a mixed-methods systematic review using the theoretical domains framework.BMC palliative care · 2026Pooled it
- Efficacy of spiritual interventions in palliative care: An umbrella review of systematic reviews.Palliative medicine · 2025Pooled it
- Psychedelic-assisted therapy for treating anxiety, depression, and existential distress in people with life-threatening diseases.The Cochrane database of systematic reviews · 2024Pooled it
- Palliative care interventions in advanced dementia.The Cochrane database of systematic reviews · 2021Pooled it
- Palliative care interventions in advanced dementia.The Cochrane database of systematic reviews · 2016Pooled it
- The Effect of an Islamic-Based Intervention on Depression and Anxiety in Malaysia.Journal of religion and health · 2022Trial
- The spiritual care intervention "In dialogue with your life story": Results of a longitudinal study on palliative clients' spiritual wellbeing.Palliative medicine · 2025Article
- Psychological interventions for emotional well-being in adults with advanced progressive life-limiting illness.The Cochrane database of systematic reviews · 2024Article
- Advanced HIV disease and health-related suffering-exploring the unmet need of palliative care.The lancet. HIV · 2023Review
- Spirituality and Children's Coping with Representation of Death During the COVID-19 Pandemic: Qualitative Research with Parents.Pastoral psychology · 2022Article
- The Source of Life: Meditation and Spirituality in Healthcare for a Comprehensive Approach to The COVID-19 Syndemic.Pastoral psychology · 2022Article
- Service Delivery Models to Maximize Quality of Life for Older People at the End of Life: A Rapid Review.The Milbank quarterly · 2019Review
- Spiritual Care in Palliative Care: A Systematic Review of the Recent European Literature.Medical sciences (Basel, Switzerland) · 2019Review
- Religiosity and Meditation Practice: Exploring Their Explanatory Power on Psychological Adjustment.Frontiers in psychology · 2019Article
- Patients' and caregivers' needs, experiences, preferences and research priorities in spiritual care: A focus group study across nine countries.Palliative medicine · 2018Article
- Should GPs provide spiritual care?The British journal of general practice : the journal of the Royal College of General Practitioners · 2017Article
- A Novel Picture Guide to Improve Spiritual Care and Reduce Anxiety in Mechanically Ventilated Adults in the Intensive Care Unit.Annals of the American Thoracic Society · 2016Article
- Article
- Spiritual beliefs near the end of life: a prospective cohort study of people with cancer receiving palliative care.Psycho-oncology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAs terminal disease progresses, health deteriorates and the end of life approaches, people may ask "Why this illness? Why me? Why now?" Such questions may invoke, rekindle or intensify spiritual or religious concerns. Although the processes by which these associations occur are poorly understood, there is some research evidence for associations that are mainly positive between spiritual and religious awareness and wellness, such as emotional health.
objectivesThis review aimed to describe spiritual and religious interventions for adults in the terminal phase of a disease and to evaluate their effectiveness on well-being. SEARCH
methodsWe searched 14 databases to November 2011, including the Cochrane Central Register of Controlled Trials and MEDLINE. SELECTION CRITERIA: We included randomised controlled trials (RCTS) if they involved adults in the terminal phase of a disease and if they evaluated outcomes for an intervention that had a spiritual or religious component. Primary outcomes were well-being, coping with the disease and quality of life. DATA COLLECTION AND ANALYSIS: In accordance with the inclusion criteria, two review authors independently screened citations. One review author extracted data which was then checked by another review author. We considered meta-analysis for studies with comparable characteristics. MAIN
resultsFive RCTs (1130 participants) were included. Two studies evaluated meditation, the others evaluated multi-disciplinary palliative care interventions that involved a chaplain or spiritual counsellor as a member of the intervention team. The studies evaluating meditation found no overall significant difference between those receiving meditation or usual care on quality of life or well-being. However, when meditation was combined with massage in the medium term it buffered against a reduction in quality of life. In the palliative care intervention studies there was no significant difference in quality of life or well-being between the trial arms. Coping with the disease was not evaluated in the studies. The quality of the studies was limited by under-reporting of design features. AUTHORS'
conclusionsWe found inconclusive evidence that interventions with spiritual or religious components for adults in the terminal phase of a disease may or may not enhance well-being. Such interventions are under-evaluated. All five studies identified were undertaken in the same country, and in the multi-disciplinary palliative care interventions it is unclear if all participants received support from a chaplain or a spiritual counsellor. Moreover, it is unclear in all the studies whether the participants in the comparative groups received spiritual or religious support, or both, as part of routine care or from elsewhere. The paucity of quality research indicates a need for more rigorous studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.