Evidence map›Paper›PMID 22592354›Full record

Trial reportJournal of general internal medicine2012

Teaching the use of respiratory inhalers to hospitalized patients with asthma or COPD: a randomized trial.

Valerie G Press, Vineet M Arora, Lisa M Shah, Stephanie L Lewis, Jeffery Charbeneau, Edward T Naureckas, Jerry A Krishnan

3 registry-linked trialsAbstract readClinical Trial, Phase IIRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of general internal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 72 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02131454 nacompletednot on this mapstarted 2013, after this paper: background citation

Impact of Inhalation Technique Training on the Course of Asthma and Chronic Obstructive Pulmonary Disease (COPD).

TypeinterventionalSponsorMedical University of WarsawRan2013 to 2016Enrolled100ConditionsAsthma, Chronic Obstructive Pulmonary DiseaseArmsInhalation technique training
NCT05025215 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Study on the Effect of Precise Aerosol Inhalation Nursing Program on Effective Sputum Excretion in Elderly Patients With Lung Surgery

TypeinterventionalSponsorThe First Affiliated Hospital of Soochow UniversityRan2021 to 2022Enrolled200ConditionsInhalationArmsPrecise Aerosol Inhalation Nursing Program, Traditional Aerosol Inhalation Nursing Method
NCT05664347 nacompletednot on this mapstarted 2020, after this paper: background citation

Video-based Teach-to-goal Intervention on Inhaler Technique on Adults With Asthma and COPD: a Randomized Controlled Trial

TypeinterventionalSponsorUniversity of JordanRan2020 to 2021Enrolled154ConditionsCOPD, Asthma, Inhaled Steroid Dependent AsthmaArmsVerbal teach to goal education, Video based teach to goal education
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Interventions to improve inhaler technique for people with asthma.The Cochrane database of systematic reviews · 2017
    Pooled it
  7. Trial
  8. Evaluating inhaler education interventions for hospitalized children with asthma: A randomized controlled trial.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023
    Trial
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  15. A randomized controlled trial to improve engagement of hospitalized patients with their patient portals.Journal of the American Medical Informatics Association : JAMIA · 2018
    Trial
  16. Trial
  17. What Really Happens in the Home: The Medication Environment of Urban, Minority Youth.The journal of allergy and clinical immunology. In practice
    Trial
  18. Review
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  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Valerie G PressSection of Hospital Medicine, Department of Medicine, University of Chicago Medical Center, 5841 S. Maryland Ave, MC 5000, W328, Chicago, IL 60637, USA. vpress@medicine.bsd.uchicago.edu
Vineet M Arora
Lisa M Shah
Stephanie L Lewis
Jeffery Charbeneau
Edward T Naureckas
Jerry A Krishnan

Funding

TRANSLATIONAL RESEARCH UNIVERSITY OF CHICAGO: CLINICAL TRIALSUL1RR024999 · NCRR · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2007 to 2011
$25.3M
CONCERT-Clinical Effectiveness Research (CONCERT-CER)RC2HL101618 · NHLBI · UNIVERSITY OF CHICAGO · PI AU, DAVID H, CARSON, SHANNON S · 2009 to 2010
$7.4M
Hospital Medicine and Economics Centers for Education & Research for TherapeuticsU18HS016967 · AHRQ · UNIVERSITY OF CHICAGO · PI MELTZER, DAVID O · 2007 to 2010
$4.0M
AHRQ HHS HS016967AHRQ HHS U18 HS016967NCRR NIH HHS UL1 RR024999NCRR NIH HHS UL1RR024999NHLBI NIH HHS HL101618NHLBI NIH HHS RC2 HL101618
6 · The paper itself

Abstract

backgroundHospitalized patients frequently misuse their respiratory inhalers, yet it is unclear what the most effective hospital-based educational intervention is for this population.

objectiveTo compare two strategies for teaching inhaler use to hospitalized patients with asthma or chronic obstructive pulmonary disease (COPD).

designA Phase-II randomized controlled clinical trial enrolled hospitalized adults with physician diagnosed asthma or COPD.

participantsHospitalized adults (age 18 years or older) with asthma or COPD.

interventionsParticipants were randomized to brief intervention [BI]: single-set of verbal and written step-by-step instructions, or, teach-to-goal [TTG]: BI plus repeated demonstrations of inhaler use and participant comprehension assessments (teach-back). MAIN MEASURES: The primary outcome was metered-dose inhaler (MDI) misuse post-intervention (<75% steps correct). Secondary outcomes included Diskus® misuse, self-reported inhaler technique confidence and prevalence of 30-day health-related events. KEY

resultsOf 80 eligible participants, fifty (63%) were enrolled (BI n=26, TTG n=24). While the majority of participants reported being confident with their inhaler technique (MDI 70%, Diskus® 94%), most misused their inhalers pre-intervention (MDI 62%, Diskus® 78%). Post-intervention MDI misuse was significantly lower after TTG vs. BI (12.5 vs. 46%, p=0.01). The results for Diskus® were similar and approached significance (25 vs. 80%, p=0.05). Participants with 30-day acute health-related events were less common in the group receiving TTG vs. BI (1 vs. 8, p=0.02).

conclusionsTTG appears to be more effective compared with BI. Patients over-estimate their inhaler technique, emphasizing the need for hospital-based interventions to correct inhaler misuse. Although TTG was associated with fewer post-hospitalization health-related events, larger, multi-centered studies are needed to evaluate the durability and clinical outcomes associated with this hospital-based education.

Indexed as

HospitalizationAdministration, InhalationAdultAgedAsthmaFemaleFollow-Up StudiesHumansMaleMetered Dose InhalersMiddle AgedPatient Education as TopicPatient ParticipationPulmonary Disease, Chronic Obstructive

Identifiers

PMID22592354
PMCPMC3445679

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.