ArticleACS applied materials & interfaces2012
Near-infrared-emitting squaraine dyes with high 2PA cross-sections for multiphoton fluorescence imaging.
Article in ACS applied materials & interfaces, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 104 citations in OpenAlex.
- Supramolecular dye nanoassemblies for advanced diagnostics and therapies.Bioengineering & translational medicine · 2024Review
- Intramolecular Charge Transfer and Ultrafast Nonradiative Decay in DNA-Tethered Asymmetric Nitro- and Dimethylamino-Substituted Squaraines.The journal of physical chemistry. A · 2023Article
- Photoacoustic Effect of Near-Infrared Absorbing Organic Molecules via Click Chemistry.Molecules (Basel, Switzerland) · 2022Article
- Shortwave infrared-absorbing squaraine dyes for all-organic optical upconversion devices.Science and technology of advanced materials · 2021Article
- Fluorescent Self-Threaded Peptide Probes for Biological Imaging.Angewandte Chemie (International ed. in English) · 2020Article
- Two-photon absorption and two-photon-induced isomerization of azobenzene compounds.RSC advances · 2020Review
- Electronic Nature of Neutral and Charged Two-Photon Absorbing Squaraines for Fluorescence Bioimaging Application.ACS omega · 2019Article
- Synthesis, Photochemical and In Vitro Cytotoxic Evaluation of New Iodinated Aminosquaraines as Potential Sensitizers for Photodynamic Therapy.Molecules (Basel, Switzerland) · 2019Article
- Nanomedicines for Near-Infrared Fluorescent Lifetime-Based Bioimaging.Frontiers in bioengineering and biotechnology · 2019Review
- Lanthanide-Doped Upconversion Nanocarriers for Drug and Gene Delivery.Nanomaterials (Basel, Switzerland) · 2018Review
- Bis{4-methylbenzyl 2-[4-(propan-2-yl)benzyl-idene]hydrazine-carbodi-thio-ato-κActa crystallographica. Section E, Crystallographic communications · 2017Article
- Synthesis of Near-Infrared Fluorescent Two-Photon-Absorbing Fluorenyl Benzothiadiazole and Benzoselenadiazole Derivatives.ACS omega · 2016Article
- A Deoxyuridine-Based Far-Red Emitting Viscosity Sensor.Molecules (Basel, Switzerland) · 2016Article
- Near-IR squaraine dye-loaded gated periodic mesoporous organosilica for photo-oxidation of phenol in a continuous-flow device.Science advances · 2015Article
- Nonlinear optical properties of multipyrrole dyes.Chemical physics letters · 2014Article
- Bovine serum albumin nanoparticles with fluorogenic near-IR-emitting squaraine dyes.ACS applied materials & interfaces · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Designed to achieve high two-photon absorptivity, new near-infrared (NIR) emitting squaraine dyes, (E)-2-(1-(2-(2-methoxyethoxy)ethyl)-5-(3,4,5-trimethoxystyryl)-1H-pyrrol-2-yl)-4-(1-(2-(2-methoxyethoxy)ethyl)-5-(3,4,5-trimethoxystyryl)-2H-pyrrolium-2-ylidene)-3-oxocyclobut-1-enolate (1) and (Z)-2-(4-(dibutylamino)-2-hydroxyphenyl)-4-(4-(dibutyliminio)-2-hydroxycyclohexa-2,5-dienylidene)-3-oxocyclobut-1-enolate (2), were synthesized and characterized. Their linear photophysical properties were investigated via UV-visible absorption spectroscopy and fluorescence spectroscopy in various solvents, while their nonlinear photophysical properties were investigated using a combination of two-photon induced fluorescence and open aperture z-scan methods. Squaraine 1 exhibited a high two-photon absorption (2PA) cross-section (δ2PA), ∼20 000 GM at 800 nm, and high photostability with the photochemical decomposition quantum yield one order of magnitude lower than Cy 5, a commercially available pentamethine cyanine NIR dye. The cytotoxicity of the squaraine dyes were evaluated in HCT 116 and COS 7 cell lines to assess the potential of these probes for biomedical imaging. The viability of both cell lines was maintained above 80% at dye concentrations up to 30 μM, indicating good biocompatibility of the probes. Finally, one-photon fluorescence microscopy (1PFM) and two-photon fluorescence microscopy (2PFM) imaging was accomplished after incubation of micelle-encapsulated squaraine probes with HCT 116 and COS 7 cells, demonstrating their potential in 2PFM bioimaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.