ArticleThe Plant cell2012
Cytosolic glyceraldehyde-3-phosphate dehydrogenases interact with phospholipase Dδ to transduce hydrogen peroxide signals in the Arabidopsis response to stress.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.
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Who cites it
117 citing papers in PubMed, 233 citations in OpenAlex.
- A small heat shock protein from Arabidopsis thaliana regulates glyceraldehyde-3-phosphate dehydrogenase in the drought tolerance.Plant cell reports · 2026Article
- Phospholipid Networks as Metabolic Hubs and Signaling Integrators in Plant Development and Stress Adaptation.Plants (Basel, Switzerland) · 2026Review
- Genome-wide identification of GAPDH gene family and functional analysis of CaGAPC2-mediated autophagy during BWYV infection in pepper.BMC genomics · 2026Article
- Implication ofInternational journal of molecular sciences · 2025Article
- Beyond glycolysis: multifunctional roles of glyceraldehyde-3-phosphate dehydrogenases in plants.Horticulture research · 2025Article
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- Cytosolic glyceraldehyde-3-phosphate dehydrogenase regulates plant stem cell maintenance under oxidative stress.Plant cell reports · 2025Article
- Characterization of the cyclic dipeptide cyclo(His-Pro) in Arabidopsis.Plant physiology · 2025Article
- A Knockout of theGenes · 2025Article
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- Perception and processing of stress signals by plant mitochondria.The Plant journal : for cell and molecular biology · 2024Review
- Omics-Driven Strategies for Developing Saline-Smart Lentils: A Comprehensive Review.International journal of molecular sciences · 2024Review
- Genomic identification and expression profiling of DMP genes in oat (Avena sativa) elucidate their responsiveness to seed aging.BMC genomics · 2024Article
- Phosphatidic acid produced by phospholipase Dα1 and Dδ is incorporated into the internal membranes but not involved in the gene expression ofFrontiers in plant science · 2024Article
- Phosphatidic acid signaling and function in nuclei.Progress in lipid research · 2024Review
- Dissection of genetic architecture of nine hazardous component traits of mainstream smoke in tobacco (Frontiers in plant science · 2024Article
- Identification and expression profiling ofFrontiers in plant science · 2024Article
- Chloroplast Auxin Efflux Mediated by ABCB28 and ABCB29 Fine-Tunes Salt and Drought Stress Responses inPlants (Basel, Switzerland) · 2023Article
- 'Autophagy · 2023Article
- The Plant Metabolic Changes and the Physiological and Signaling Functions in the Responses to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2023Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive oxygen species (ROS) are produced in plants under various stress conditions and serve as important mediators in plant responses to stresses. Here, we show that the cytosolic glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenases (GAPCs) interact with the plasma membrane-associated phospholipase D (PLDδ) to transduce the ROS hydrogen peroxide (H(2)O(2)) signal in Arabidopsis thaliana. Genetic ablation of PLDδ impeded stomatal response to abscisic acid (ABA) and H(2)O(2), placing PLDδ downstream of H(2)O(2) in mediating ABA-induced stomatal closure. To determine the molecular link between H(2)O(2) and PLDδ, GAPC1 and GAPC2 were identified to bind to PLDδ, and the interaction was demonstrated by coprecipitation using proteins expressed in Escherichia coli and yeast, surface plasmon resonance, and bimolecular fluorescence complementation. H(2)O(2) promoted the GAPC-PLDδ interaction and PLDδ activity. Knockout of GAPCs decreased ABA- and H(2)O(2)-induced activation of PLD and stomatal sensitivity to ABA. The loss of GAPCs or PLDδ rendered plants less responsive to water deficits than the wild type. The results indicate that the H(2)O(2)-promoted interaction of GAPC and PLDδ may provide a direct connection between membrane lipid-based signaling, energy metabolism and growth control in the plant response to ROS and water stress.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.