Evidence map›Paper›PMID 22589299›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2012

Consequences of NMO-IgG binding to aquaporin-4 in neuromyelitis optica.

Andrea Rossi, Julien Ratelade, Marios C Papadopoulos, Jeffrey L Bennett, A S Verkman

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  3. Article
  4. Plant and Mammal Aquaporins: Same but Different.International journal of molecular sciences · 2018
    Review
  5. Article
  6. AQP4e-Based Orthogonal Arrays Regulate Rapid Cell Volume Changes in Astrocytes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  7. Neuromyelitis Optica: Deciphering a Complex Immune-Mediated Astrocytopathy.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2017
    Review
  8. Review
  9. Review
  10. Article
  11. Molecular pathogenesis of neuromyelitis optica.International journal of molecular sciences · 2012
    Review
  12. Article
  13. Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies.The international journal of biochemistry & cell biology · 2012
    Review
  14. Aquaporin 4 and neuromyelitis optica.The Lancet. Neurology · 2012
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Andrea Rossi
Julien Ratelade
Marios C Papadopoulos
Jeffrey L Bennett
A S Verkman

Funding

WATER AND NON-ELECTROLYTE TRANSPORT IN RENAL VESICLESR01DK035124 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VERKMAN, ALAN S · 1986 to 2014
$1.4M
NIDDK NIH HHS R01 DK035124
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAquaporin 4AstrocytesBiomarkersImmunoglobulin GNeuromyelitis OpticaAquaporin 4BiomarkersImmunoglobulin G

Identifiers

PMID22589299
PMCPMC3386066

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.