ArticleBiointerphases2012
Design and fabrication of tubular scaffolds via direct writing in a melt electrospinning mode.
Article in Biointerphases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Hybrid SES-MEW Scaffold Strategies: A Narrative Review of Multi-Scale Fiber Architectures for Soft and Hard Tissue Engineering.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Dynamic assessment of a humanized bone tumour microenvironment reveals insights into osteosarcoma primary tumour remodelling and lung metastases.Scientific reports · 2025Article
- Advances in Polypyrrole Nanofiber Composites: Design, Synthesis, and Performance in Tissue Engineering.Materials (Basel, Switzerland) · 2025Review
- Guidance on biomaterials for periodontal tissue regeneration: Fabrication methods, materials and biological considerations.Dental materials : official publication of the Academy of Dental Materials · 2025Review
- Humanized In Vivo Bone Tissue Engineering: In Vitro Preculture Conditions Control the Structural, Cellular, and Matrix Composition of Humanized Bone Organs.Advanced healthcare materials · 2025Article
- An Intelligent and Efficient Workflow for Path-Oriented 3D Bioprinting of Tubular Scaffolds.3D printing and additive manufacturing · 2024Article
- Harnessing the Regenerative Potential of Fetal Mesenchymal Stem Cells and Endothelial Colony-Forming Cells in the Biofabrication of Tissue-Engineered Vascular Grafts (TEVGs).Journal of tissue engineering and regenerative medicine · 2024Article
- Integrating Fused Deposition Modeling and Melt Electrowriting for Engineering Branched Vasculature.Biomedicines · 2023Article
- Flexible, Suturable, and Leak-free Scaffolds for Vascular Tissue Engineering Using Melt Spinning.ACS biomaterials science & engineering · 2023Article
- Harnessing Biofabrication Strategies to Re-Surface Osteochondral Defects: Repair, Enhance, and Regenerate.Biomimetics (Basel, Switzerland) · 2023Review
- Unveiling the potential of melt electrowriting in regenerative dental medicine.Acta biomaterialia · 2023Review
- The Technological Advancement to Engineer Next-Generation Stent-Grafts: Design, Material, and Fabrication Techniques.Advanced healthcare materials · 2022Review
- Recycling and Reutilizing Polymer Waste via Electrospun Micro/Nanofibers: A Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Mechanically reinforced biotubes for arterial replacement and arteriovenous grafting inspired by architectural engineering.Science advances · 2022Article
- Compositions and Structural Geometries of Scaffolds Used in the Regeneration of Cleft Palates: A Review of the Literature.Polymers · 2022Review
- Convergence of Machine Vision and Melt Electrowriting.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Near-Field Electrospinning and Melt Electrowriting of Biomedical Polymers-Progress and Limitations.Polymers · 2021Review
- Article
- Polymers for Melt Electrowriting.Advanced healthcare materials · 2021Review
- Recent Advances in Vertical Alveolar Bone Augmentation Using Additive Manufacturing Technologies.Frontiers in bioengineering and biotechnology · 2021Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flexible tubular structures fabricated from solution electrospun fibers are finding increasing use in tissue engineering applications. However it is difficult to control the deposition of fibers due to the chaotic nature of the solution electrospinning jet. By using non-conductive polymer melts instead of polymer solutions the path and collection of the fiber becomes predictable. In this work we demonstrate the melt electrospinning of polycaprolactone in a direct writing mode onto a rotating cylinder. This allows the design and fabrication of tubes using 20 μm diameter fibers with controllable micropatterns and mechanical properties. A key design parameter is the fiber winding angle, where it allows control over scaffold pore morphology (e.g. size, shape, number and porosity). Furthermore, the establishment of a finite element model as a predictive design tool is validated against mechanical testing results of melt electrospun tubes to show that a lesser winding angle provides improved mechanical response to uniaxial tension and compression. In addition, we show that melt electrospun tubes support the growth of three different cell types in vitro and are therefore promising scaffolds for tissue engineering applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.