ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2012
The social patterns of a biological risk factor for disease: race, gender, socioeconomic position, and C-reactive protein.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Socioeconomic status and inflammation: a meta-analysis.Molecular psychiatry · 2020Pooled it
- The Relation Between Systemic Inflammation and the Menopause Transition: The Study of Women's Health Across the Nation.The Journal of clinical endocrinology and metabolism · 2025Article
- Racial/Ethnic Differences in Biological Aging and Their Life Course Socioeconomic Determinants: The 2016 Health and Retirement Study.Journal of aging and health · 2023Article
- Racial/ethnic variations in inflammatory markers: exploring the role of sleep duration and sleep efficiency.Journal of behavioral medicine · 2022Article
- Correlates of Elevated C-Reactive Protein Among Black Older Adults: Evidence From the Health and Retirement Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Student Debt and Cardiovascular Disease Risk Among U.S. Adults in Early Mid-Life.American journal of preventive medicine · 2022Article
- Individuals with both higher recent negative affect and physical pain have higher levels of C-reactive protein.Brain, behavior, & immunity - health · 2022Article
- Spatial Dynamics and Multiscale Regression Modelling of Population Level Indicators for COVID-19 Spread in Malaysia.International journal of environmental research and public health · 2022Article
- AST to Platelet Ratio Index (APRI) is an easy-to-use predictor score for cardiovascular risk in metabolic subjects.Scientific reports · 2021Article
- Race, Gender, and Socioeconomic Variations in C-Reactive Protein Using the Health and Retirement Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021Article
- The Association Between Loneliness and Inflammation: Findings From an Older Adult Sample.Frontiers in behavioral neuroscience · 2021Article
- Early Social Origins of Biological Risks for Men and Women in Later Life.Journal of health and social behavior · 2020Article
- Racial Differences in Elevated C-Reactive Protein Among US Older Adults.Journal of the American Geriatrics Society · 2020Article
- Epigenetic Changes Associated with Early Life Experiences: Saliva, A Biospecimen for DNA Methylation Signatures.Current genomics · 2018Article
- Negative and positive affect as predictors of inflammation: Timing matters.Brain, behavior, and immunity · 2018Article
- The Relationship Between Religious and Psychospiritual Measures and an Inflammation Marker (CRP) in Older Adults Experiencing Life Event Stress.Journal of religion and health · 2018Article
- Concurrent Social Disadvantages and Chronic Inflammation: The Intersection of Race and Ethnicity, Gender, and Socioeconomic Status.Journal of racial and ethnic health disparities · 2018Article
- Elevated inflammation in association with alcohol abuse among Blacks but not Whites: results from the MIDUS biomarker study.Journal of behavioral medicine · 2018Article
- Systemic Inflammation Is Associated With Longitudinal Changes in Cognitive Performance Among Urban Adults.Frontiers in aging neuroscience · 2018Article
- The Influence of Social Conditions Across the Life Course on the Human Gut Microbiota: A Pilot Project With the Wisconsin Longitudinal Study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveUnderstand the links between race and C-reactive protein (CRP), with special attention to gender differences and the role of class and behavioral risk factors as mediators.
methodThis study utilizes the National Social Life, Health, and Aging Project data, a nationally representative study of older Americans aged 57-85 to explore two research questions. First, what is the relative strength of socioeconomic versus behavioral risk factors in explaining race differences in CRP levels? Second, what role does gender play in understanding race differences? Does the relative role of socioeconomic and behavioral risk factors in explaining race differences vary when examining men and women separately?
resultsWhen examining men and women separately, socioeconomic and behavioral risk factor mediators vary in their importance. Indeed, racial differences in CRP among men aged 57-74 are little changed after adjusting for both socioeconomic and behavioral risk factors with levels 35% higher for black men as compared to white men. For women aged 57-74, however, behavioral risk factors explain 30% of the relationship between race and CRP. DISCUSSION: The limited explanatory power of socioeconomic position and, particularly, behavioral risk factors, in elucidating the relationship between race and CRP among men, signals the need for research to examine additional mediators, including more direct measures of stress and discrimination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.