ArticleClinical rheumatology2012
Predictors of health-related quality of life and fatigue in systemic sclerosis: evaluation of the EuroQol-5D and FACIT-F assessment tools.
Article in Clinical rheumatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 41 citations in OpenAlex.
- Concurrent Validity Between EQ-5D and HRQ-6D Measures in Patients with Different Primary Diagnoses.Journal of clinical medicine · 2024Article
- Prevalence and Outcomes of Gastrointestinal Manifestations in an Australian Scleroderma Cohort.Arthritis care & research · 2024Article
- Systemic Sclerosis Quality of Life Questionnaire (SScQoL): translation into Turkish and assessing its psychometric properties.Clinical rheumatology · 2023Article
- Association of pain and clinical factors on disability and quality of life in systemic sclerosis: A cross-sectional study from Turkish League Against Rheumatism Network.Archives of rheumatology · 2023Article
- Minimal Clinically Important Differences (MCID) for the Functional Assessment of Chronic Illness Therapy Fatigue Scale in Patients with Systemic Sclerosis.International journal of environmental research and public health · 2022Article
- Article
- Functional disability and health-related quality of life among systemic sclerosis patients in Bangladesh.BMC rheumatology · 2022Article
- Fatigue and activity management education for individuals with systemic sclerosis: Adaptation and feasibility study of an intervention for a rare disease.Musculoskeletal care · 2022Article
- High prevalence of fatigue in patients with Takayasu arteritis: a case-control study in a Brazilian centre.Rheumatology advances in practice · 2022Article
- Fatigue Predicts Future Reduced Social Participation, not Reduced Physical Function or Quality of Life in People with Systemic Sclerosis.Journal of scleroderma and related disorders · 2021Article
- Cultural adaptation and validation of the Systemic Sclerosis Quality of Life questionnaire into Arabic language.Clinical rheumatology · 2021Article
- Predictors of health-related quality of life in musculoskeletal disease patients: a longitudinal analysis.Therapeutic advances in musculoskeletal disease · 2021Article
- Factors associated with quality of life in systemic sclerosis: a cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease.Arthritis research & therapy · 2019Article
- Severe gastrointestinal disease in very early systemic sclerosis is associated with early mortality.Rheumatology (Oxford, England) · 2019Article
- Common measure of quality of life for people with systemic sclerosis across seven European countries: a cross-sectional study.Annals of the rheumatic diseases · 2018Article
- Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis: the European Scleroderma Observational Study.Rheumatology (Oxford, England) · 2018Observational
- Clinical significance and usefulness of rehabilitation for systemic sclerosis.Journal of scleroderma and related disorders · 2018Review
- Social/economic costs and health-related quality of life in patients with scleroderma in Europe.The European journal of health economics : HEPAC : health economics in prevention and care · 2016Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluates predictors of health-related quality of life (HRQoL) and fatigue in systemic sclerosis (SSc) using two novel self-report indices. A cross-sectional study of patients with SSc was undertaken using a postal questionnaire including the EuroQol-5Domain health questionnaire (EQ-5D™), Functional Assessment of Chronic Illness Therapy-Fatigue scale (FACIT-F) and the Scleroderma Health Assessment Questionnaire (SHAQ). The EQ-5D assesses five domains of health quality and is quantified as a time trade-off (TTO) value and patient global assessment (0-100 visual analogue scale [VAS]). The FACIT-F is a 13-item questionnaire (0-52 scale). Higher scores for both the EQ-5D and FACIT-F indicate better health. Case notes were scrutinised for patient demographics, disease duration, serology and clinical phenotype. Sixty-eight patients (60 females, mean age 62.6 years) completed the questionnaires. Fatigue correlated closely with HRQoL (r (s) = 0.78 and 0.77 for FACIT-F vs. EQ-5D VAS and TTO respectively, p < 0.01) and disability (r (s) = -0.74 for FACIT-F vs. HAQ-DI, p < 0.01). Pain was the most frequently reported health problem (80 %) in the EQ-5D. HRQoL also correlated closely with disability (r (s) = 0.83 for EQ-5D vs. HAQ-DI, p < 0.01). SHAQ-VAS scores correlated well with the FACIT-F, EQ-5D and HAQ-DI scores (p < 0.05 for all comparisons). Of the patient demographics and clinical disease associations, only the absence of upper gastrointestinal complications was associated with better levels of fatigue, HRQoL and function. There is a strong correlation between disability, fatigue and HRQoL measured using self-reports, possibly reflecting similarly perceived health beliefs amongst patients across outcomes. There was little association between self-report indices and patient demographics and/or clinical phenotype.
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