ArticleVeterinary research2012
Leukocidin genes lukF-P83 and lukM are associated with Taphylococcus aureus clonal complexes 151, 479 and 133 isolated from bovine udder infections in Thuringia, Germany.
Article in Veterinary research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 78 citations in OpenAlex.
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- Gram-positive ESKAPE pathogens in Germany: A comprehensive analysis of occurrence and resistance development in animal, food, and environmental sources.One health (Amsterdam, Netherlands) · 2025Review
- The Host Adaptation of Staphylococcus aureus to Farmed Ruminants in New Zealand, With Special Reference to Clonal Complex 1.Environmental microbiology reports · 2025Article
- Risk factors for dairy cows mastitis in Algeria, antibiotic resistance and molecular typing of the causative Staphylococcus aureus.Veterinary research communications · 2024Article
- Bacteriophage-driven emergence and expansion of Staphylococcus aureus in rodent populations.PLoS pathogens · 2024Article
- Virulence Mechanisms of Staphylococcal Animal Pathogens.International journal of molecular sciences · 2023Review
- Genome sequencing and comparative genomic analysis of bovine mastitis-associated Staphylococcus aureus strains from India.BMC genomics · 2023Article
- Whole genome sequence-based analysis ofFrontiers in microbiology · 2023Article
- Survey of Staphylococcus aureus carriage by free-living red deer (Cervus elaphus): Evidence of human and domestic animal lineages.Transboundary and emerging diseases · 2022Article
- Usefulness of molecular typing methods for epidemiological and evolutionary studies ofSaudi journal of biological sciences · 2022Review
- Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives.BMC veterinary research · 2022Review
- Staphylococcus aureus isolates from Eurasian Beavers (Castor fiber) carry a novel phage-borne bicomponent leukocidin related to the Panton-Valentine leukocidin.Scientific reports · 2021Article
- Bovine milk somatic cell transcriptomic response to Staphylococcus aureus is dependent on strain genotype.BMC genomics · 2021Article
- Molecular Characterization ofPathogens (Basel, Switzerland) · 2021Article
- Fatal exudative dermatitis in island populations of red squirrels (Microbial genomics · 2021Article
- Article
- Genomic Analysis ofFrontiers in microbiology · 2021Article
- Genomic analysis of European bovine Staphylococcus aureus from clinical versus subclinical mastitis.Scientific reports · 2020Article
- Characterization ofFrontiers in veterinary science · 2020Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Staphylococcus aureus is one of the most important causal agents of bovine mastitis. Population studies on bovine Staphylococcus aureus isolates have identified considerable genetic heterogeneity among strains causing mastitis. The aim of this study was to investigate the contribution of different clonal complexes and the occurrence of virulence factors and resistance determinants within bovine Staphylococcus aureus isolates.A total of 189 Staphylococcus aureus isolates obtained from milk samples of 34 dairy herds in the German Federal State of Thuringia were characterised by microarray technology.The isolates were assigned to eleven different clonal complexes with CC151, CC479 and CC133 being dominant (together 80.5%). The methicillin resistance gene mecA was found in four isolates (2.1%), which belonged to CC398. Enterotoxin genes could be detected in 79.3% of analysed Staphylococcus aureus and 19 isolates (10.1%) harboured a distinct allele of the toxic shock syndrome toxin gene, tst-RF122. The most striking finding of the present study was that almost all except one isolate (151/152) belonging to CC151, CC479 and CC133 harboured the leukocidin genes lukF-P83 and lukM, whereas no further isolates from other lineages possessed these genes.The consistent occurrence of lukF-P83/lukM in the dominating clonal complexes suggests an essential role of this leukocidin in the etiology of bovine mastitis.
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