ArticleScientific reports2012
Formation of nano-bio-complex as nanomaterials dispersed in a biological solution for understanding nanobiological interactions.
Article in Scientific reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Effect of dopamine-functionalization, charge and pH on protein corona formation around TiONanoscale · 2022Article
- The polysaccharide chitosan facilitates the isolation of small extracellular vesicles from multiple biofluids.Journal of extracellular vesicles · 2021Article
- Combined Toxicity of Metal Nanoparticles: Comparison of Individual and Mixture Particles Effect.Advances in experimental medicine and biology · 2021Article
- In Vitro and In Vivo Models for Evaluating the Oral Toxicity of Nanomedicines.Nanomaterials (Basel, Switzerland) · 2020Review
- Nanoparticle corona artefacts derived from specimen preparation of particle suspensions.Scientific reports · 2020Article
- Rutile nano-bio-interactions mediate dissimilar intracellular destiny in human skin cells.Nanoscale advances · 2019Article
- Comparative functional dynamics studies on the enzyme nano-bio interface.International journal of nanomedicine · 2018Article
- A review on ZnO-based electrical biosensors for cardiac biomarker detection.Future science OA · 2017Review
- Adsorption of bovine serum albumin on silicon dioxide nanoparticles: Impact of pH on nanoparticle-protein interactions.Biointerphases · 2017Article
- Shape and surface properties of titanate nanomaterials influence differential cellular uptake behavior and biological responses in THP-1 cells.Biochemistry and biophysics reports · 2017Article
- Trojan-Like Internalization of Anatase Titanium Dioxide Nanoparticles by Human Osteoblast Cells.Scientific reports · 2016Article
- Serum Proteins Enhance Dispersion Stability and Influence the Cytotoxicity and Dosimetry of ZnO Nanoparticles in Suspension and Adherent Cancer Cell Models.Nanoscale research letters · 2015Article
- Chip based single cell analysis for nanotoxicity assessment.The Analyst · 2014Review
- Identification and avoidance of potential artifacts and misinterpretations in nanomaterial ecotoxicity measurements.Environmental science & technology · 2014Article
- Using a holistic approach to assess the impact of engineered nanomaterials inducing toxicity in aquatic systems.Journal of food and drug analysis · 2014Review
- Size- and time-dependent alteration in metabolic activities of human hepatic cytochrome P450 isozymes by gold nanoparticles via microsomal coincubations.Nanoscale research letters · 2014Article
- Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review.Archives of toxicology · 2013Review
- Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity.ACS nano · 2013Article
- Effects of serum on cytotoxicity of nano- and micro-sized ZnO particles.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2013Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information on how cells interface with nanomaterials in biological environments has important implications for the practice of nanomedicine and safety consideration of nanomaterials. However, our current understanding of nanobiological interactions is still very limited. Here, we report the direct observation of nanomaterial bio-complex formation (other than protein corona) from nanomaterials dispersed in biologically relevant solutions. We observed highly selective binding of the components of cell culture medium and phosphate buffered saline to ZnO and CuO nanoparticles, independent of protein molecules. Our discoveries may provide new insights into the understanding of how cells interact with nanomaterials.
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Registered trials
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