ArticleFrontiers in immunology2012
Macroautophagy Regulation during HIV-1 Infection of CD4+ T Cells and Macrophages.
Article in Frontiers in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Article
- Review
- The Interplay of HIV and Autophagy in Early Infection.Frontiers in microbiology · 2021Review
- Review
- HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.JCI insight · 2017Article
- Viruses and the autophagy pathway.Virology · 2015Review
- Autophagy restricts HIV-1 infection by selectively degrading Tat in CD4+ T lymphocytes.Journal of virology · 2015Article
- Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells.Blood · 2014Article
- Detection of the HIV-1 minus-strand-encoded antisense protein and its association with autophagy.Journal of virology · 2013Article
- The cellular autophagy pathway modulates human T-cell leukemia virus type 1 replication.Journal of virology · 2013Article
- Autophagy for Better or Worse during Infectious Diseases.Frontiers in immunology · 2013Article
- Characterization of HIV-1 infection and innate sensing in different types of primary human monocyte-derived macrophages.Mediators of inflammation · 2013Article
- HIV-1 and the immune response to TB.Future virology · 2013Article
- Review
- Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses.Journal of biomedical science · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autophagy is an intracellular mechanism whereby pathogens, particularly viruses, are destroyed in autolysosomes after their entry into targets cells. Therefore, to survive and replicate in host cells, viruses have developed multiple strategies to either counteract or exploit this process. The aim of this review is to outline the known relationships between HIV-1 and autophagy in CD4+ T lymphocytes and macrophages, two main HIV-1 cell targets. The differential regulation of autophagy in these two cell-types is highlighted and its potential consequences in terms of viral replication and physiopathology discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.