ArticleAdvances in nutrition (Bethesda, Md.)2012
The role of milk sialyllactose in intestinal bacterial colonization.
Article in Advances in nutrition (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Human colostrum oligosaccharides modulate major immunologic pathways of immature human intestine.Mucosal immunology · 2014Trial
- Biosynthesis of human milk oligosaccharides (HMOs) in glycoengineered human cells.Glycobiology · 2026Article
- Deletion of Endogenous Neuregulin-4 Limits Adaptive Immunity During Interleukin-10 Receptor-Neutralizing Colitis.Inflammatory bowel diseases · 2023Article
- 3'sialyllactose and 6'sialyllactose enhance performance in endurance-type exercise through metabolic adaptation.Food science & nutrition · 2023Article
- Molecular Dynamics Simulations Reveal the Conformational Transition of GH33 Sialidases.International journal of molecular sciences · 2023Article
- 6'-sialyllactose ameliorates the ototoxic effects of the aminoglycoside antibiotic neomycin in susceptible mice.Frontiers in immunology · 2023Article
- Exposure to 3'Sialyllactose-Poor Milk during Lactation Impairs Cognitive Capabilities in Adulthood.Nutrients · 2021Article
- Immunomodulatory Effects of Human Colostrum and Milk.Pediatric gastroenterology, hepatology & nutrition · 2021Review
- Microbiota control of maternal behavior regulates early postnatal growth of offspring.Science advances · 2021Article
- Comparison of Different Labeling Techniques for the LC-MS Profiling of Human Milk Oligosaccharides.Frontiers in chemistry · 2021Article
- Akkermansia muciniphila uses human milk oligosaccharides to thrive in the early life conditions in vitro.Scientific reports · 2020Article
- Immunomodulation by Human Milk Oligosaccharides: The Potential Role in Prevention of Allergic Diseases.Frontiers in immunology · 2020Review
- Effect of Zn Addition on the Cd-Containing Anaerobic Fermentation Process: Biodegradation and Microbial Communities.International journal of environmental research and public health · 2019Article
- Process Analysis of Anaerobic Fermentation Exposure to Metal Mixtures.International journal of environmental research and public health · 2019Article
- Synthesis and Characterization of Sialylated Lactose- and Lactulose-Derived Oligosaccharides by Trypanosoma cruzi Trans-sialidase.Journal of agricultural and food chemistry · 2019Article
- 3'-Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis.Journal of cellular and molecular medicine · 2018Article
- Article
- Human milk oligosaccharides protect bladder epithelial cells against uropathogenic Escherichia coli invasion and cytotoxicity.The Journal of infectious diseases · 2014Article
- Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes.Glycobiology · 2013Article
- Introduction to the symposium.Advances in nutrition (Bethesda, Md.) · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Milk oligosaccharides influence the composition of intestinal microbiota and thereby mucosal inflammation. Some of the major milk oligosaccharides are α2,3-sialyllactose (3SL) and α2,6-sialyllactose, which are mainly produced by the sialyltransferases ST3GAL4 and ST6GAL1, respectively. Recently, we showed that mice fed milk deficient in 3SL were more resistant to dextran sulfate sodium-induced colitis. By contrast, the exposure to milk containing or deficient in 3SL had no impact on the development of mucosal leukocyte populations. Milk 3SL mainly affected the colonization of the intestine by clostridial cluster IV bacteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.