ReviewAdvances in nutrition (Bethesda, Md.)2012
Influence of dairy product and milk fat consumption on cardiovascular disease risk: a review of the evidence.
Review in Advances in nutrition (Bethesda, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 10 syntheses or guidelines pooled it, 275 citations in OpenAlex.
- Dairy Consumption and Risk of Cardiovascular and Bone Health Outcomes in Adults: An Umbrella Review and Updated Meta-Analyses.Nutrients · 2025Pooled it
- The effect of fermented dairy intake and abdominal obesity in adults: a systematic review and dose-response meta-analysis of cohort studies.Eating and weight disorders : EWD · 2025Pooled it
- Comprehensive Investigation on Associations between Dietary Intake and Blood Levels of Fatty Acids and Colorectal Cancer Risk.Nutrients · 2023Pooled it
- Biomarkers of dairy fat intake, incident cardiovascular disease, and all-cause mortality: A cohort study, systematic review, and meta-analysis.PLoS medicine · 2021Pooled it
- Evidence for a causal association between milk intake and cardiometabolic disease outcomes using a two-sample Mendelian Randomization analysis in up to 1,904,220 individuals.International journal of obesity (2005) · 2021Pooled it
- Intake of dairy products and associations with major atherosclerotic cardiovascular diseases: a systematic review and meta-analysis of cohort studies.Scientific reports · 2021Pooled it
- Perspective: The Role of Beverages as a Source of Nutrients and Phytonutrients.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Cheese Consumption and Risk of All-Cause Mortality: A Meta-Analysis of Prospective Studies.Nutrients · 2017Pooled it
- Pooled it
- Milk Consumption and Mortality from All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Meta-Analysis.Nutrients · 2015Pooled it
- Trial
- Dietary changes associated with improvement of metabolic syndrome components in postmenopausal women receiving two different nutrition interventions.Menopause (New York, N.Y.) · 2015Trial
- Impact of milk consumption on cardiometabolic risk in postmenopausal women with abdominal obesity.Nutrition journal · 2015Trial
- Multiomics Insights Linking Personal Care Products Exposure to Serum Lipid Profiles in Older Adults: The China BAPE Study.Environmental health perspectives · 2026Article
- Beyond Saturated Fat: A Four-Dimensional Framework for Understanding Milk Fat in Human Health.Comprehensive reviews in food science and food safety · 2026Review
- Lipid accumulation product (LAP): a key indicator for metabolic dysregulation and inflammatory status in obesity.Scientific reports · 2026Article
- Association between gut microbiota diet index and cardiovascular disease in US adults: a cross-sectional study of NHANES 2007-2018.BMC cardiovascular disorders · 2026Article
- The impact of dietary interventions on cardiometabolic health.Cardiovascular diabetology · 2025Review
- The Role of Dairy in Human Nutrition: Myths and Realities.Nutrients · 2025Review
- Dairy consumption and premature coronary artery disease onset: Iran premature coronary artery disease (IPAD) study insights.Scientific reports · 2025Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although evidence has linked the consumption of saturated fat (SF) to increased LDL levels and an increased risk of the development of cardiovascular disease (CVD), recent findings have indicated that the link between CVD and SF may be less straightforward than originally thought. This may be due to the fact that some food sources high in SF contain an array of saturated and unsaturated fatty acids, each of which may differentially affect lipoprotein metabolism, as well as contribute significant amounts of other nutrients, which may alter CVD risk. The purpose of this review is to examine the published research on the relationship between milk fat containing dairy foods and cardiovascular health. The findings indicate that the majority of observational studies have failed to find an association between the intake of dairy products and increased risk of CVD, coronary heart disease, and stroke, regardless of milk fat levels. Results from short-term intervention studies on CVD biomarkers have indicated that a diet higher in SF from whole milk and butter increases LDL cholesterol when substituted for carbohydrates or unsaturated fatty acids; however, they may also increase HDL and therefore might not affect or even lower the total cholesterol:HDL cholesterol ratio. The results from the review also indicate that cheese intake lowers LDL cholesterol compared with butter of equal milk fat content. In addition, the review highlights some significant gaps in the research surrounding the effects of full-fat dairy on CVD outcomes, pointing to the need for long-term intervention studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.