Evidence map›Paper›PMID 22585724›Full record

ArticleJournal of medical virology2012

The viral etiology of an influenza-like illness during the 2009 pandemic.

S D Thiberville, L Ninove, V Vu Hai, E Botelho-Nevers, C Gazin, L Thirion, N Salez, X de Lamballerie, R Charrel, P Brouqui

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. SARS-CoV-2 infection in children in Moscow in 2020: clinical features and impact on circulation of other respiratory viruses: SARS-CoV-2 infection in children in Moscow in 2020.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
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  5. Variations in respiratory pathogen carriage among a homeless population in a shelter for men in Marseille, France, March-July 2020: cross-sectional 1-day surveys.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
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  6. Epidemiology of respiratory pathogen carriage in the homeless population within two shelters in Marseille, France, 2015-2017: cross sectional 1-day surveys.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2019
    Article
  7. Article
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  9. Update on Human Rhinovirus and Coronavirus Infections.Seminars in respiratory and critical care medicine · 2016
    Review
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  16. Review
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  19. Circulation of respiratory viruses among pilgrims during the 2012 Hajj pilgrimage.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013
    Article
  20. Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

S D ThibervilleUMR 190 (Aix-Marseille Univ IRD EHESP), Emergence des Pathologies Virales, Marseille, France.
L Ninove
V Vu Hai
E Botelho-Nevers
C Gazin
L Thirion
N Salez
X de Lamballerie
R Charrel
P Brouqui
Aix-Marseille Université · FRInstitut de Recherche pour le Développement · FRÉcole des Hautes Études en Santé Publique · FRHung Vuong Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many viruses are known to cause influenza-like illness (ILI); however, in nearly 50% of patients, the etiologic agent remains unknown. The distribution of viruses in patients with ILI was investigated during the 2009 A/H1N1 influenza pandemic (A/H1N1p). From June 2009 to January 2010, 660 patients with suspected influenza were questioned and examined, and nasal swabs were collected. All patient samples were tested for influenza virus, and 286 negative nasal swabs were tested further for 18 other respiratory viruses using real-time RT-PCR. Two waves of ILI were observed in the epidemic curve (weeks 35-42 and 42-49). At least eight viruses co-circulated during this period: human rhinovirus (HRV) (58), parainfluenza 1-4 viruses (PIV) (9), human Coronavirus (hCoV) OC43 (9), enterovirus (5), adenovirus (AdV) (4), and human metapneumovirus (hMPV) (2); however, 204 samples remained negative for all viruses tested. ILI symptoms, according to the Centers for Disease Control and Prevention criteria for ILI definition, were reported in 75% of cases. These patients had positive swabs for A/H1N1p, HRV, hCoV-OC43, PIV, AdV, and hMPV without significant difference with non-ILI patients. This study found that many respiratory viruses circulated during this period and that the A/H1N1p did not impact on the kinetics of other respiratory viruses. The proportion of non-documented cases remains high. ILI could not distinguish A/H1N1p infection from that due to other respiratory viruses. However, in multivariate anlaysis, cough, chills, hyperemia, and dyspnea were associated significantly with influenza virus versus other respiratory viruses.

Indexed as

AdolescentAdultAgedChildFemaleHumansInfluenza, HumanMaleMiddle AgedNosePrevalenceReal-Time Polymerase Chain ReactionRespiratory Tract DiseasesReverse Transcriptase Polymerase Chain ReactionRNA VirusesYoung Adult

Identifiers

PMID22585724
PMCPMC7166619
OpenAlexW2081574945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.