ArticleCancer discovery2012
Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing.
Article in Cancer discovery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Tumor-Informed Approach Improved ctDNA Detection Rate in Resected Pancreatic Cancer.International journal of molecular sciences · 2022Article
- Detection of Lung Cancer Cells in Solutions Using a Terahertz Chemical Microscope.Sensors (Basel, Switzerland) · 2021Article
- Identification of Potential Genomic Alterations and the circRNA-miRNA-mRNA Regulatory Network in Primary and Recurrent Synovial Sarcomas.Frontiers in molecular biosciences · 2021Article
- Touch imprint cytology with massively parallel sequencing (TIC-seq): a simple and rapid method to snapshot genetic alterations in tumors.Cancer medicine · 2016Article
- Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue.PloS one · 2015Article
- Performance of amplicon-based next generation DNA sequencing for diagnostic gene mutation profiling in oncopathology.Cellular oncology (Dordrecht, Netherlands) · 2014Article
- Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics.PloS one · 2014Article
- Navigating the rapids: the development of regulated next-generation sequencing-based clinical trial assays and companion diagnostics.Frontiers in oncology · 2014Review
- DNA qualification workflow for next generation sequencing of histopathological samples.PloS one · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most tumor samples available for clinical genotyping are formalin-fixed and paraffin-embedded (FFPE), but there has been relatively little published on the suitability of such samples for next-generation sequencing approaches. A new study by Wagle and colleagues shows that a combination of hybridization-capture and deep sequencing yields high-quality data from FFPE specimens.
Indexed as
Identifiers
22585165What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.