ArticleGeneral thoracic and cardiovascular surgery2012
Gender influence in isolated coronary artery bypass graft surgery: a propensity match score analysis of early outcomes.
Article in General thoracic and cardiovascular surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Female sex is associated with short-term mortality in coronary artery bypass grafting patients: A propensity-matched analysis.Heliyon · 2025Article
- Sex differences in outcomes of patients undergoing on-pump coronary artery bypass grafting surgery.PloS one · 2024Observational
- Female gender does not have any significant impact on the early postoperative outcomes after coronary artery bypass grafting: a propensity-matched analysis.Indian journal of thoracic and cardiovascular surgery · 2023Article
- Higher Surgery and Recovery Room Air Pressures Associated with Reduced Surgical Site Infection Risk.World journal of surgery · 2021Article
- The impact of age on outcomes of coronary artery bypass grafting.Journal of cardiothoracic surgery · 2020Article
- Article
- Gender differences in outcomes following isolated coronary artery bypass grafting: long-term results.Journal of cardiothoracic surgery · 2016Article
- Female Gender and Differences in Outcome after Isolated Coronary Artery Bypass Graft Surgery: Does Age Play a Role?PloS one · 2016Article
- Early and Mid-term Outcomes in Female Patients Undergoing Isolated Conventional Coronary Surgery.Journal of cardiovascular and thoracic research · 2014Article
- Gender difference in long- and short-term outcomes of off-pump coronary endarterectomy.Annals of cardiac anaesthesiaArticle
- Factors influencing transfusion requirement in patients undergoing first-time, elective coronary artery bypass graft surgery.Asian journal of transfusion scienceArticle
- Are the Early Postoperative Outcomes of Coronary Artery Bypass Grafting Surgery in Elderly Women Worse Compared to Men's?Brazilian journal of cardiovascular surgeryObservational
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe female gender has been shown as high-risk factor for mortality and morbidity. We sought to assess the influence of female gender on coronary artery bypass graft (CABG) surgery from our own experience.
methodsThis is a retrospective analysis of prospectively collected database from a single centre. Patients were grouped according to gender and potential differences in pre-operative, intra-operative and post-operative factors were explored. Significant high-risk factors were then fitted in a multivariate model to account for differences in predicting gender influence on surgical outcomes.
resultsTwo thousand eight hundred and four consecutive patients underwent isolated first-time CABG between February 2000 and December 2008; 562 (20%) patients were females. Pre-operatively, females were more likely to have significant comorbidities (age, congestive cardiac failure, hypercholesterolemia, hypertension, ischemic heart disease, peripheral vascular disease, pre-op arrhythmias, small body surface area and poor ejection fraction (p < 0.001)) consistent with higher Euroscore (p > 0.0001) and more urgent surgery (p < 0.002). Intra-operatively, they showed less extent pattern of disease requiring less bypass and cross-clamp time (p < 0.001). Observed surgical mortality was significantly higher in females (3.6 vs. 2.1%, p < 0.042); however, after adjusting for propensity score and significant factors identified in multivariate models, females only independently predicted a higher wound infection, lower neurological complications, lower rate of re-sternotomy, longer hospital stay and post-surgery stay (p < 0.01).
conclusionsDespite higher risk profile and higher observed surgical mortality, early outcomes in females were similar to their matched males' counterpart in isolated CABG surgery. Females were associated with higher incidence of wound infections but lower rate of neurological complications.
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