ArticleAllergy and asthma proceedings
Assessment of the association between atopic conditions and tympanostomy tube placement in children.
Article in Allergy and asthma proceedings. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Article
- Artificial intelligence biomarker detects high-risk childhood asthma subgroup for respiratory infections and exacerbations.The Journal of allergy and clinical immunology · 2025Article
- Sinonasal Intervention Reduces the Need for Pressure Equalization Tube Placement in Atopic Adults.The Laryngoscope · 2025Article
- Allergic rhinitis and asthma: drivers of otitis media and associated tympanostomy tube placement.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Establishing an expert consensus for the operational definitions of asthma-associated infectious and inflammatory multimorbidities for computational algorithms through a modified Delphi technique.BMC medical informatics and decision making · 2021Article
- Review of otitis media microbiome studies: What do they tell us?Laryngoscope investigative otolaryngology · 2020Review
- Altered Middle Ear Microbiome in Children With Chronic Otitis Media With Effusion and Respiratory Illnesses.Frontiers in cellular and infection microbiology · 2019Article
- Early Identification of Childhood Asthma: The Role of Informatics in an Era of Electronic Health Records.Frontiers in pediatrics · 2019Review
- Application of a Natural Language Processing Algorithm to Asthma Ascertainment. An Automated Chart Review.American journal of respiratory and critical care medicine · 2017Article
- Asthma and the Risk of Rheumatoid Arthritis: An Insight into the Heterogeneity and Phenotypes of Asthma.Tuberculosis and respiratory diseases · 2017Review
- Asthma and Risk of Appendicitis in Children: A Population-Based Case-Control Study.Academic pediatrics · 2017Article
- Adult Atopic Dermatitis with Comorbid Atopic Disease is Associated with Increased Risk of Infections: A Population-Based Cross-Sectional Study.Dermatology and therapy · 2017Article
- Interaction Between Allergy and Middle Ear Infection.Current allergy and asthma reports · 2016Review
- Asthma and risk of breakthrough varicella infection in children.Allergy and asthma proceedings · 2016Article
- Asthma as a risk factor for zoster in adults: A population-based case-control study.The Journal of allergy and clinical immunology · 2016Article
- Development and initial testing of Asthma Predictive Index for a retrospective study: an exploratory study.The Journal of asthma : official journal of the Association for the Care of Asthma · 2015Article
- Risks for infection in patients with asthma (or other atopic conditions): is asthma more than a chronic airway disease?The Journal of allergy and clinical immunology · 2014Review
- What does tympanostomy tube placement in children teach us about the association between atopic conditions and otitis media?Current allergy and asthma reports · 2014Review
- Asthma and severity of 2009 novel H1N1 influenza: a population-based case-control study.The Journal of asthma : official journal of the Association for the Care of Asthma · 2013Article
- Asthma and the immune response to MMR vaccine viruses in Somali immigrant children: a cross-sectional retrospective cohort study.Primary care respiratory journal : journal of the General Practice Airways Group · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
This study assesses the relationship between otitis media and atopic conditions in children by comparing the incidence of tympanostomy tube placement between children with and without atopic conditions: asthma, allergic rhinitis, and atopic dermatitis. Study subjects were a cohort of 323 healthy children who participated in a study of vaccine response. All episodes of tympanostomy tube placement and physician diagnoses of allergic rhinitis and atopic dermatitis were collected through comprehensive medical record review. Asthma status was ascertained through application of established criteria. We compared incidence rates of tympanostomy tube placement between children with and without atopic conditions. We fitted data to a Poisson regression model to calculate relative risk ratios (RRs) and their corresponding 95% confidence intervals (95% CI). Three subjects were excluded who did not have parental authorization for using records for research. Of the remaining 320 subjects, 170 (53%) were male subjects, 268 (94%) were white, 124 (39%) were asthmatic patients, and 20 (6%) had tympanostomy tube placement. Children with asthma before the index date of tympanostomy tube placement were more likely to have tympanostomy tube placement compared with those without asthma (RR, 19.33; 95% CI, 11.41; 32.75; p < 0.001). We found a similar association between asthma ever (before or after index date) and the incidence of tympanostomy tube placement (RR, 1.53; 95% CI, 0.93-2.53; p = 0.095). This was true for children with allergic rhinitis compared with those without allergic rhinitis (RR, 1.70; 95% CI, 1.01-2.86; p = 0.007). Atopic dermatitis was not associated with the incidence of tympanostomy tube placement. Asthma or allergic rhinitis may be unrecognized risk factors for recurrent or persistent otitis media. However, given the small sample size of the study, a cohort study with a larger sample size is necessary.
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