Evidence map›Paper›PMID 22583845›Full record

ArticleHead & neck oncology2012

Reconstruction of scalp defects with the radial forearm free flap.

Larissa Sweeny, Brendan Eby, J Scott Magnuson, William R Carroll, Eben L Rosenthal

Expression of concernOpen access · hybridAbstract read
In one paragraph

Article in Head & neck oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Squamous Cell Carcinoma of Scalp: Our Experience in a Single Tertiary Care Centre.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Free Tissue Reconstruction of the Scalp.Seminars in plastic surgery · 2019
    Review
  12. Scalp Rotation Flap for Reconstruction of Complex Soft Tissue Defects.Journal of neurological surgery. Part B, Skull base · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Larissa SweenyDepartment of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Alabama at Birmingham, Alabama, USA.
Brendan Eby
J Scott Magnuson
William R Carroll
Eben L Rosenthal
University of Alabama at Birmingham · US

Funding

Research Training Program in Surgical OncologyT32CA091078 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KENNEDY, GREGORY DEAN · 2002 to 2017
$4.8M
CD147 as a Novel Target in Head and Neck CancerR01CA142637 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROSENTHAL, EBEN L. · 2010 to 2014
$1.3M
NCI NIH HHS 2 T32 CA091078-09NCI NIH HHS R01 CA142637NCI NIH HHS T32 CA091078
6 · The paper itself

Abstract

backgroundAdvanced and recurrent cutaneous squamous cell carcinoma of the scalp and forehead require aggressive surgical excision often resulting in complex defects requiring reconstruction. This study evaluates various microvascular free flap reconstructions in this patient population, including the rarely utilized radial forearm free flap. PATIENTS AND

methodsA retrospective review of patients undergoing free flap surgeries (n = 47) of the scalp between 1997 and 2011 were included. Patients were divided primarily into two cohorts: a new primary lesion (n = 21) or recurrence (n = 26). Factors examined include patient demographics, indication for surgery, defect, type of flap used, complications (major and minor), and outcomes.

resultsThe patients were primarily male (n = 34), with a mean age of 67 years (25-91). A total of 58 microvascular free flap reconstructions were performed (radial forearm free flap: n = 28, latissimus dorsi: n = 20, rectus abdominis: n = 9, scapula: n = 1). Following reconstruction with a radial forearm free flap, duration of hospitalization was shorter (P = 0.04) and complications rates were similar (P = 0.46). Donor site selection correlated with defect area (P < 0.001), but not with the extent of skull defect (P = 0.70). Larger defect areas correlated with higher complications rates (P = 0.03) and longer hospitalization (P = 0.003). Patients were more likely to require multiple reconstructions if referred for a recurrent lesions (P = 0.01) or received prior radiation therapy (P = 0.02).

conclusionAdvanced and recurrent malignancies of the scalp are aggressive and challenging to treat. The radial forearm free flap is an underutilized free flap in the reconstruction of complex scalp defects.

Indexed as

Free Tissue FlapsAdultAgedAged, 80 and overCarcinoma, Squamous CellFemaleForearmHead and Neck NeoplasmsHumansMaleMiddle AgedPlastic Surgery ProceduresRetrospective StudiesScalpTissue Transplantation

Identifiers

PMID22583845
PMCPMC3414765
OpenAlexW2110593207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.