ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2012
Independent association of younger age with hemoptysis in adults with pulmonary tuberculosis.
Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Hepatobiliary Nontuberculous Mycobacterial Infection Mimicking Malignancy in a Patient with Anti-Interferon-γ Autoantibodies.Diagnostics (Basel, Switzerland) · 2026Article
- Association of Single Nucleotide Polymorphism rs17580 with Smoking and Pulmonary Tuberculosis.Journal of healthcare engineering · 2022Article
- Association of serum antibodies against the Mycobacterium avium complex and hemoptysis: a cross-sectional study.BMC infectious diseases · 2021Article
- Hemoptysis requiring bronchial artery embolization in patients with nontuberculous mycobacterial lung disease.BMC pulmonary medicine · 2019Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe risk factors for mild to moderate hemoptysis in patients with pulmonary tuberculosis (PTB) are not entirely clear.
objectiveTo evaluate the independent association of risk factors with the occurrence of hemoptysis in PTB patients.
designCross-sectional study of adult patients newly diagnosed with microbiologically proven PTB in a New York City hospital. Patients were categorized into subjects with and without hemoptysis and compared using univariate analysis. Independent associations of variables with hemoptysis were estimated using multivariate logistic regression.
resultsOf 194 subjects with PTB, 44 (23%) had hemoptysis. In univariate analysis, subjects with hemoptysis were significantly younger (P = 0.003), and more likely to be undocumented foreign-born (P = 0.038) compared to subjects without hemoptysis. In multivariate analysis, only younger age was independently associated with hemoptysis. This association was significant for a continuous decrease in age per year, or per decade (adjusted OR 1.59, P = 0.003).
conclusionsYounger age is an independent risk factor for hemoptysis in PTB. It is conceivable that a stronger inflammatory response in younger than in older age could contribute to pulmonary pathogenesis and injury in PTB.
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