ArticleBMC genomics2012
Identification of avian W-linked contigs by short-read sequencing.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 0 citations in OpenAlex.
- SCiMS: Sex Calling in Metagenomic Sequences.bioRxiv : the preprint server for biology · 2026Article
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- State of the art on the physical mapping of the Y-chromosome in the Bovidae and comparison with other species - A review.Animal bioscience · 2022Article
- Telomere-to-telomere assembly of a fish Y chromosome reveals the origin of a young sex chromosome pair.Genome biology · 2021Article
- X-Linked Signature of Reproductive Isolation in Humans is Mirrored in a Howler Monkey Hybrid Zone.The Journal of heredity · 2020Article
- Identification of Y chromosome markers in the eastern three-lined skink (Bassiana duperreyi) using in silico whole genome subtraction.BMC genomics · 2020Article
- Characterization of the First W-Specific Protein-Coding Gene for Sex Identification inFrontiers in genetics · 2020Article
- Comparative analyses of three swallow species (Aves, Passeriformes, Hirundinidae): Insights on karyotype evolution and genomic organization.Genetics and molecular biology · 2020Article
- Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds.Genome biology and evolution · 2019Article
- The evolutionary history of grey wolf Y chromosomes.Molecular ecology · 2019Article
- A new approach for comprehensively describing heterogametic sex chromosomes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Article
- Avian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators.Nature genetics · 2017Article
- Article
- Genome-Wide Search Identifies 1.9 Mb from the Polar Bear Y Chromosome for Evolutionary Analyses.Genome biology and evolution · 2015Article
- A transcriptome derived female-specific marker from the invasive Western mosquitofish (Gambusia affinis).PloS one · 2015Article
- Independent stratum formation on the avian sex chromosomes reveals inter-chromosomal gene conversion and predominance of purifying selection on the W chromosome.Evolution; international journal of organic evolution · 2014Article
- Tracing the evolution of amniote chromosomes.Chromosoma · 2014Review
- Article
- Avian sex, sex chromosomes, and dosage compensation in the age of genomics.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2014Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe female-specific W chromosomes and male-specific Y chromosomes have proven difficult to assemble with whole-genome shotgun methods, creating a demand for new approaches to identify sequence contigs specific to these sex chromosomes. Here, we develop and apply a novel method for identifying sequences that are W-specific.
resultsUsing the Illumina Genome Analyzer, we generated sequence reads from a male domestic chicken (ZZ) and mapped them to the existing female (ZW) genome sequence. This method allowed us to identify segments of the female genome that are underrepresented in the male genome and are therefore likely to be female specific. We developed a Bayesian classifier to automate the calling of W-linked contigs and successfully identified more than 60 novel W-specific sequences.
conclusionsOur classifier can be applied to improve heterogametic whole-genome shotgun assemblies of the W or Y chromosome of any organism. This study greatly improves our knowledge of the W chromosome and will enhance future studies of avian sex determination and sex chromosome evolution.
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