ArticleDevelopmental neurorehabilitation2012
The psychiatric phenotype in triple X syndrome: new hypotheses illustrated in two cases.
Article in Developmental neurorehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 16 citations in OpenAlex.
- Triple X syndrome: Psychiatric disorders and impaired social functioning as a risk factor.European psychiatry : the journal of the Association of European Psychiatrists · 2022Article
- Social functioning and emotion recognition in adults with triple X syndrome.BJPsych open · 2021Article
- Diminished Ovarian Reserve in Girls and Adolescents with Trisomy X Syndrome.Reproductive sciences (Thousand Oaks, Calif.) · 2020Article
- Early neurodevelopmental and medical profile in children with sex chromosome trisomies: Background for the prospective eXtraordinarY babies study to identify early risk factors and targets for intervention.American journal of medical genetics. Part C, Seminars in medical genetics · 2020Review
- Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Review
- Double trisomy 48,XXX,+18 with multiple dysmorphic features.World journal of pediatrics : WJP · 2015Article
- Unravelling the Impact of an Additional Sex Chromosome in an Adult Female.Journal of human reproductive sciencesArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTriple X syndrome (47,XXX or trisomy X) is a relatively frequent cytogenetic condition with a large variety of physical and behavioural phenotypes.
methodTwo adult patients with a triple X karyotype are described.
resultsTheir karyotype was unknown until some years ago. What these patients have in common is that they were diagnosed with a broader autism phenotype, they were sexually abused, they suffer from psychotic illness and they show challenging behaviour, suicidality and a decline in occupational capacity. DISCUSSION: These gene-environment interactions are discussed. Gene-environment interactions may explain the variety of behavioural and psychiatric phenotypes in triple X syndrome. Ongoing atypical development in adults is hypothesized.
conclusionsGene-environment interactions and ongoing atypical development in adults should be taken into account in research concerning the psychiatric phenotype of developmental disorders, especially those involving triple X syndrome.
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