ReviewJournal of microscopy2012
Microscopy beyond the diffraction limit using actively controlled single molecules.
Review in Journal of microscopy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed.
- Exploring Transient States of PAmKate to Enable Improved Cryogenic Single-Molecule Imaging.Journal of the American Chemical Society · 2024Article
- Exploring transient states of PAmKate to enable improved cryogenic single-molecule imaging.bioRxiv : the preprint server for biology · 2024Article
- Nanometer-scale distribution of PD-1 in the melanoma tumor microenvironment.Journal of radiology and oncology · 2023Article
- Improved immunoassay sensitivity and specificity using single-molecule colocalization.Nature communications · 2022Article
- Biochemical Interactions through Microscopic Techniques: Structural and Molecular Characterization.Polymers · 2022Review
- Ground state depletion microscopy as a tool for studying microglia-synapse interactions.Journal of neuroscience research · 2021Article
- Cryogenic Super-Resolution Fluorescence and Electron Microscopy Correlated at the Nanoscale.Annual review of physical chemistry · 2021Review
- Super-resolution Microscopy with Single Molecules in Biology and Beyond-Essentials, Current Trends, and Future Challenges.Journal of the American Chemical Society · 2020Review
- Addressing systematic errors in axial distance measurements in single-emitter localization microscopy.Optics express · 2020Article
- Deep learning in single-molecule microscopy: fundamentals, caveats, and recent developments [Invited].Biomedical optics express · 2020Review
- The Emerging Role of the Mammalian Glycocalyx in Functional Membrane Organization and Immune System Regulation.Frontiers in cell and developmental biology · 2020Review
- A bird's-eye view of deep learning in bioimage analysis.Computational and structural biotechnology journal · 2020Review
- Single-molecule detection on a portable 3D-printed microscope.Nature communications · 2019Article
- Conjugation of Fab' Fragments with Fluorescent Dyes for Single-Molecule Tracking On Live Cells.Bio-protocol · 2019Article
- 3D sub-diffraction imaging in a conventional confocal configuration by exploiting super-linear emitters.Nature communications · 2019Article
- Viewpoint: Localization Microscopy of Single Molecules Enhanced by 3D Imaging and Light Sheet Illumination.Journal of physics D: Applied physics · 2019Article
- Membrane water for probing neuronal membrane potentials and ionic fluxes at the single cell level.Nature communications · 2018Article
- Alternative reagents to antibodies in imaging applications.Biophysical reviews · 2017Review
- Three-Dimensional Localization of Single Molecules for Super-Resolution Imaging and Single-Particle Tracking.Chemical reviews · 2017Review
- Measurement-based estimation of global pupil functions in 3D localization microscopy.Optics express · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In this short review, the general principles are described for obtaining microscopic images with resolution beyond the optical diffraction limit with single molecules. Although it has been known for several decades that single-molecule emitters can blink or turn on and off, in recent work the addition of on/off control of molecular emission to maintain concentrations at very low levels in each imaging frame combined with sequential imaging of sparse subsets has enabled the reconstruction of images with resolution far below the optical diffraction limit. Single-molecule active control microscopy provides a powerful window into information about nanoscale structures that was previously unavailable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.