ArticlePsychosomatic medicine2012
Revealing causal heterogeneity using time series analysis of ambulatory assessments: application to the association between depression and physical activity after myocardial infarction.
Article in Psychosomatic medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- An individual participant data meta-analysis of how physical activity relates to affective well-being in daily life.Nature human behaviour · 2026Pooled it
- Pooled it
- Self-monitoring and personalized feedback based on the experiencing sampling method as a tool to boost depression treatment: a protocol of a pragmatic randomized controlled trial (ZELF-i).BMC psychiatry · 2018Trial
- Group, Subgroup and Person-Specific Longitudinal Associations Between Physical Activity and Affect in Individuals With and Without Depressive and Anxiety Disorders.International journal of methods in psychiatric research · 2026Article
- A Novel Deep Learning Approach for Forecasting Myocardial Infarction Occurrences with Time Series Patient Data.Journal of medical systems · 2024Article
- Article
- On the Role of Psychoneuroimmunology in Oral Medicine.International dental journal · 2022Review
- Within-day bidirectional associations between physical activity and affect: A real-time ambulatory study in persons with and without depressive and anxiety disorders.Depression and anxiety · 2022Article
- Continuous-Time Modeling of the Bidirectional Relationship Between Incidental Affect and Physical Activity.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022Article
- Article
- Personalizing cognitive behavioral therapy for cancer-related fatigue using ecological momentary assessments followed by automated individual time series analyses: A case report series.Internet interventions · 2021Article
- Sociodemographic, Health and Lifestyle, Sampling, and Mental Health Determinants of 24-Hour Motor Activity Patterns: Observational Study.Journal of medical Internet research · 2021Observational
- Reflections on psychological resilience: a comparison of three conceptually different operationalizations in predicting mental health.European journal of psychotraumatology · 2021Observational
- Measuring psychopathology as it unfolds in daily life: addressing key assumptions of intensive longitudinal methods in the TRAILS TRANS-ID study.BMC psychiatry · 2020Article
- Temporal Associations of Daily Changes in Sleep and Depression Core Symptoms in Patients Suffering From Major Depressive Disorder: Idiographic Time-Series Analysis.JMIR mental health · 2020Article
- The temporal order of fluctuations in atopic disease symptoms and attention-deficit/hyperactivity disorder symptoms: a time-series study in ADHD patients.European child & adolescent psychiatry · 2020Article
- Time series analyses with psychometric data.PloS one · 2020Article
- Single-Subject Research in Psychiatry: Facts and Fictions.Frontiers in psychiatry · 2020Review
- Foundations of idiographic methods in psychology and applications for psychotherapy.Clinical psychology review · 2019Review
- A Positive Causal Influence of IL-18 Levels on the Risk of T2DM: A Mendelian Randomization Study.Frontiers in genetics · 2019Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveStudies in psychosomatic medicine are characterized by analyses that typically compare groups. This nomothetic approach leads to conclusions that apply to the average group member but not necessarily to individual patients. Idiographic studies start at the individual patient and are suitable to study associations that differ between time points or between individuals. We illustrate the advantages of the idiographic approach in analyzing ambulatory assessments, taking the association between depression and physical activity after myocardial infarction as an example.
methodsFive middle-aged men who had myocardial infarction with mild to moderate symptoms of depression were included in this study. Four of these participants monitored their physical activity and depressive symptoms during a period of 2 to 3 months using a daily self-registration form. The time series of each individual participant were investigated using vector autoregressive modeling, which enables the analysis of temporal dynamics between physical activity and depression.
resultsWe found causal heterogeneity in the association between depression and physical activity. Participants differed in the predominant direction of effect, which was either from physical activity to depression (n = 1, 85 observations, unstandardized effect size = -0.183, p = .03) or from depression to physical activity (n = 2, 65 and 59 observations, unstandardized effect sizes = -0.038 and -0.381, p < .001 and p = .04). Also, the persistency of effects differed among individuals.
conclusionsVector autoregressive models are suitable in revealing causal heterogeneity and can be easily used to analyze ambulatory assessments. We suggest that these models might bridge the gap between science and clinical practice by translating epidemiological results to individual patients.
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