Evidence map›Paper›PMID 22582313›Full record

Trial reportPsychosomatic medicine2012

Individual and neighborhood socioeconomic status and inflammation in Mexican American women: what is the role of obesity?

Linda C Gallo, Addie L Fortmann, Karla Espinosa de Los Monteros, Paul J Mills, Elizabeth Barrett-Connor, Scott C Roesch, Karen A Matthews

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Psychosomatic medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00387166 (Cardiovascular Risk Disparities), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00387166 completednot on this map

Cardiovascular Risk Disparities: Socio-Emotional Pathways

TypeobservationalSponsorSan Diego State UniversityRan2006 to 2010Enrolled304ConditionsHypertension, Cardiovascular Disease, Metabolic Disorders
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Physiologic and psychosocial changes of the menopause transition in US Latinas: a narrative review.Climacteric : the journal of the International Menopause Society · 2021
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Observational
  15. Article
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  18. Observational
  19. Article
  20. A three-decade evolution to transdisciplinary research: community health research in California-Mexico border communities.Progress in community health partnerships : research, education, and action · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Linda C GalloDepartment of Psychology, San Diego StateUniversity, San Diego, CA, USA. lcgallo@sciences.sdsu.edu
Addie L Fortmann
Karla Espinosa de Los Monteros
Paul J Mills
Elizabeth Barrett-Connor
Scott C Roesch
Karen A Matthews
Norwegian Womens Public Health Association · NOBridge University · SS

Funding

SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE (UL1)UL1RR025774 · NCRR · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2008 to 2011
$16.3M
TRAINING COREP20MD002293 · NIMHD · SAN DIEGO STATE UNIVERSITY · PI GALLO, LINDA C · 2007 to 2011
$5.7M
Cardiovascular Risk Disparities: Socioemotional PathwaysR01HL081604 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI GALLO, LINDA C · 2006 to 2009
$2.4M
NCRR NIH HHS UL1 RR025774NHLBI NIH HHS 1R01HL081604NHLBI NIH HHS R01 HL081604NIMHD NIH HHS P20 MD002293
6 · The paper itself

Abstract

objectiveInflammation may represent a biological mechanism underlying associations of socioeconomic status (SES) with cardiovascular disease. We examined relationships of individual and neighborhood SES with inflammatory markers in Mexican American women and evaluated contributions of obesity and related heath behaviors to these associations.

methodsTwo hundred eighty-four Mexican American women (mean age = 49.74 years) were recruited from socioeconomically diverse South San Diego communities. Women completed measures of sociodemographic characteristics and health behaviors, and underwent a physical examination with fasting blood draw for assay of plasma C-reactive protein (CRP), interleukin 6 (IL-6), and soluble intercellular adhesion molecule 1 (sICAM-1). Neighborhood SES was extracted from the US Census Bureau 2000 database.

resultsIn multilevel models, a 1-standard deviation higher individual or neighborhood SES related to a 27.35% and 23.56% lower CRP level (p values < .01), a 7.04% and 5.32% lower sICAM-1 level (p values < .05), and a 10.46% (p < .05) and 2.40% lower IL-6 level (not significant), respectively. Controlling for individual SES, a 1-standard deviation higher neighborhood SES related to a 18.05% lower CRP level (p = .07). Differences in body mass index, waist circumference, and dietary fat consumption contributed significantly to SES-inflammation associations.

conclusionsThe findings support a link between SES and inflammatory markers in Mexican American women and implicate obesity and dietary fat in these associations. Additional effects of neighborhood SES were not statistically significant; however, these findings should be viewed tentatively due to the small sample size to evaluate contextual effects. Trial Registration ClinicalTrials.gov identifier: NCT00387166.

Indexed as

Social ClassBody Mass IndexCaliforniaCardiovascular DiseasesC-Reactive ProteinDietary FatsFemaleHealth BehaviorHumansInflammationIntercellular Adhesion Molecule-1Interleukin-6Linear ModelsMexican AmericansMiddle AgedMultilevel AnalysisC-Reactive ProteinDietary FatsIntercellular Adhesion Molecule-1Interleukin-6

Identifiers

PMID22582313
PMCPMC3372661
OpenAlexW2004969237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.