ArticleApplied and environmental microbiology2012
Cold atmospheric air plasma sterilization against spores and other microorganisms of clinical interest.
Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
79 citing papers in PubMed, 355 citations in OpenAlex.
- Non-thermal plasma assisted reduction of hexavalent chromium(vi) using hydrazine hydrate: impact on wheat (RSC advances · 2026Article
- Cold Atmospheric Plasma in Biomedicine and Pharmacology: Multidisciplinary Perspectives on Therapeutic Applications.ACS pharmacology & translational science · 2026Review
- The power of neutralization: the critical step for the accurate antimicrobial potential of plasma-activated water.Frontiers in microbiology · 2026Article
- Investigating the effects of microwave plasma on bacterial cell structures, viability, and membrane integrity.Scientific reports · 2025Article
- Cold atmospheric plasma drives USP49/HDAC3 axis mediated ferroptosis as a novel therapeutic strategy in endometrial cancer via reinforcing lactylation dependent p53 expression.Journal of translational medicine · 2025Article
- The Genetic Expression Difference of A2058 Cells Treated by Plasma Direct Exposure and Plasma-Treated Medium and the Appropriate Treatment Strategy.Biomedicines · 2025Article
- Bioaerosol Inactivation by a Cold Plasma Ionizer Coupled with an Electrostatic Precipitator.Microorganisms · 2024Article
- Synergistic effects of oxidative and acid stress on bacterial membranes of Escherichia coli and Staphylococcus simulans.Communications biology · 2024Article
- The pH acidity and nitrate accumulation by plasma discharge enhanced the growth and phytochemicals of soybean sprouts grown in reused water.Food chemistry: X · 2024Article
- Bacterial Decontamination of Water-Containing Objects Using Piezoelectric Direct Discharge Plasma and Plasma Jet.Biomolecules · 2024Article
- No-ozone cold plasma induces apoptosis in human neuroblastoma cell line via increased intracellular reactive oxygen species (ROS).BMC complementary medicine and therapies · 2024Article
- Two separate mechanisms are involved in membrane permeabilization during lipid oxidation.Biophysical journal · 2023Article
- Innovative Application of Cold Plasma Technology in Meat and Its Products.Food science of animal resources · 2023Review
- Influence of electric potential-induced by atmospheric pressure plasma on cell response.Scientific reports · 2023Article
- Basic research and clinical exploration of cold atmospheric plasma for skin wounds.Bioengineering & translational medicine · 2023Article
- The Role of Cold Atmospheric Plasma in Wound Healing Processes in Critically Ill Patients.Journal of personalized medicine · 2023Review
- Impact of needle-point bipolar ionization system in the reduction of bioaerosols in collective transport.The Science of the total environment · 2023Article
- Cold Atmospheric Plasma: A Promising and Safe Therapeutic Strategy for Atopic Dermatitis.International archives of allergy and immunology · 2023Review
- Plasma degradation of contaminated PPE: an energy-efficient method to treat contaminated plastic waste.Npj Materials degradation · 2023Article
- Pyocyanin biosynthesis protects Pseudomonas aeruginosa from nonthermal plasma inactivation.Microbial biotechnology · 2022Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical cold atmospheric surface microdischarge (SMD) plasma operating in ambient air has promising properties for the sterilization of sensitive medical devices where conventional methods are not applicable. Furthermore, SMD plasma could revolutionize the field of disinfection at health care facilities. The antimicrobial effects on Gram-negative and Gram-positive bacteria of clinical relevance, as well as the fungus Candida albicans, were tested. Thirty seconds of plasma treatment led to a 4 to 6 log(10) CFU reduction on agar plates. C. albicans was the hardest to inactivate. The sterilizing effect on standard bioindicators (bacterial endospores) was evaluated on dry test specimens that were wrapped in Tyvek coupons. The experimental D(23)(°)(C) values for Bacillus subtilis, Bacillus pumilus, Bacillus atrophaeus, and Geobacillus stearothermophilus were determined as 0.3 min, 0.5 min, 0.6 min, and 0.9 min, respectively. These decimal reduction times (D values) are distinctly lower than D values obtained with other reference methods. Importantly, the high inactivation rate was independent of the material of the test specimen. Possible inactivation mechanisms for relevant microorganisms are briefly discussed, emphasizing the important role of neutral reactive plasma species and pointing to recent diagnostic methods that will contribute to a better understanding of the strong biocidal effect of SMD air plasma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.