Evidence map›Paper›PMID 22581449›Full record

ReviewJournal of molecular neuroscience : MN2012

Role of neurotrophins in the development and function of neural circuits that regulate energy homeostasis.

Samira Fargali, Masato Sadahiro, Cheng Jiang, Amy L Frick, Tricia Indall, Valeria Cogliani, Jelle Welagen, Wei-Jye Lin, Stephen R Salton

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular neuroscience : MN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Effects of Strength Training on BDNF in Healthy Young Adults.International journal of environmental research and public health · 2022
    Review
  9. Article
  10. Review
  11. Increased ciliary neurotrophic factor in blood serum and lacrimal fluid as a potential biomarkers of focal epilepsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  12. Article
  13. Methylation ofFrontiers in integrative neuroscience · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. cAMP-inducible coactivator CRTC3 attenuates brown adipose tissue thermogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Samira FargaliFishberg Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.
Masato Sadahiro
Cheng Jiang
Amy L Frick
Tricia Indall
Valeria Cogliani
Jelle Welagen
Wei-Jye Lin
Stephen R Salton
Icahn School of Medicine at Mount Sinai · US

Funding

VGF function in depression and antidepressant treatmentR01MH086499 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SALTON, STEPHEN R · 2010 to 2014
$2.1M
Association of 7q22.1 gene VGF with obesity and leanessR01DK071308 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SALTON, STEPHEN R · 2005 to 2008
$1.4M
Human VGF Polymorphisms and DepressionR21MH083496 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SALTON, STEPHEN R · 2008 to 2009
$339k
Human VGF Polymorphisms and DepressionR33MH083496 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SALTON, STEPHEN R · 2010 to 2010
$254k
NIDDK NIH HHS R01 DK071308NIMH NIH HHS R01 MH086499NIMH NIH HHS R21 MH083496NIMH NIH HHS R33 MH083496
6 · The paper itself

Abstract

Members of the neurotrophin family, including nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5, and other neurotrophic growth factors such as ciliary neurotrophic factor and artemin, regulate peripheral and central nervous system development and function. A subset of the neurotrophin-dependent pathways in the hypothalamus, brainstem, and spinal cord, and those that project via the sympathetic nervous system to peripheral metabolic tissues including brown and white adipose tissue, muscle and liver, regulate feeding, energy storage, and energy expenditure. We briefly review the role that neurotrophic growth factors play in energy balance, as regulators of neuronal survival and differentiation, neurogenesis, and circuit formation and function, and as inducers of critical gene products that control energy homeostasis.

Indexed as

Adipose TissueAnimalsAutonomic Fibers, PostganglionicBasal MetabolismBrain StemCorticotropin-Releasing HormoneEatingEnergy MetabolismGene Expression RegulationGlucocorticoidsHomeostasisHumansHypothalamusNerve Growth FactorsNeural PathwaysNeuropeptidesCorticotropin-Releasing HormoneGlucocorticoidsNerve Growth FactorsNeuropeptidesReceptors, Nerve Growth Factor

Identifiers

PMID22581449
PMCPMC3480664
OpenAlexW2056184901

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.