ReviewCurrent hypertension reports2012
Antihypertensive treatment and sexual dysfunction.
Review in Current hypertension reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 91 citations in OpenAlex.
- Reproductive and sexual health concerns in gastrointestinal illness: a narrative review.Translational gastroenterology and hepatology · 2025Review
- Under-Prescription of Drugs in the Elderly Population of Western Romania: An Analysis Based on STOPP/START Version 2 Criteria.Journal of clinical medicine · 2024Article
- Effects of Pharmaceutical Substances with Obesogenic Activity on Male Reproductive Health.International journal of molecular sciences · 2024Review
- Causal effects of hypertension on risk of erectile dysfunction: A two-sample Mendelian randomization study.Frontiers in cardiovascular medicine · 2023Article
- Drug-Induced Sexual Dysfunction: An Analysis of Reports to a National Pharmacovigilance Database.Drug safety · 2022Article
- Quality of Life, Sexual Functioning and Chronic Disease: A Comparative Study with Portuguese Women without Chronic Disease, and Women with Diabetes Type 1 and 2, and Arterial Hypertension.International journal of sexual health : official journal of the World Association for Sexual Health · 2022Article
- Increased risk of testosterone deficiency is associated with the systemic immune-inflammation index: a population-based cohort study.Frontiers in endocrinology · 2022Article
- Comparison of Effect of Nebivolol and Bisoprolol on Sexual Function of Hypertensive Female Patients.Cureus · 2021Article
- Hypertension and erectile dysfunction: The role of endovascular therapy in Asia.Journal of clinical hypertension (Greenwich, Conn.) · 2021Review
- Hypertension and Reproduction.Current hypertension reports · 2020Review
- Type 2 diabetes complications and comorbidity in Sub-Saharan Africans.EClinicalMedicine · 2019Article
- Changes in Sexual Functioning in Women and Men in the 5 Years After Bariatric Surgery.JAMA surgery · 2019Article
- Sexualıty and marıtal adjustment ın women wıth hypertensıon ın Turkey: how culture affects sex.Journal of human hypertension · 2019Article
- Blood pressure, antihypertensive medication use, and risk of erectile dysfunction in men with type I diabetes.Journal of hypertension · 2019Article
- Corino de Andrade disease: mechanisms and impact on reproduction.JBRA assisted reproduction · 2017Review
- Sexual functioning of men and women with severe obesity before bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Observational
- β-Blockade use for Traumatic Injuries and Immunomodulation: A Review of Proposed Mechanisms and Clinical Evidence.Shock (Augusta, Ga.) · 2016Review
- Article
- The Effect of Acetyl Salicylic Acid Induced Nitric Oxide Synthesis in the Normalization of Hypertension through the Stimulation of Renal Cortexin Synthesis and by the Inhibition of Dermcidin Isoform 2, A Hypertensive Protein Production.International journal of biomedical science : IJBS · 2014Article
- A review of the positive and negative effects of cardiovascular drugs on sexual function: a proposed table for use in clinical practice.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sexual dysfunction is frequently encountered in hypertensive patients. Available data indicates that sexual dysfunction is more frequent in treated than in untreated patients, generating the hypothesis that antihypertensive therapy might be associated with sexual dysfunction. Several lines of evidence suggest that differences between antihypertensive drugs exist regarding their effects on sexual function. Older antihypertensive drugs (diuretics, beta blockers) exert detrimental effects on erectile function whereas newer drugs (nebivolol, angiotensin receptor blockers) have neutral or even beneficial effects. Phosphodiesterase (PDE)-5 inhibitors are effective in hypertensive patients and can be safely administered even when multidrug regimes are used. Precautions need to be taken with alpha blockers or patients with uncontrolled high-risk hypertension, while co-administration with nitrates is contraindicated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.