ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2012
The effect of biomaterials and antifungals on biofilm formation by Candida species: a review.
Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 81 citations in OpenAlex.
- Biofilm-related characteristics ofFrontiers in cellular and infection microbiology · 2026Article
- Arginine-Derived Cationic Surfactants Containing Phenylalanine and Tryptophan: Evaluation of Antifungal Activity, Biofilm Eradication, Cytotoxicity, and Ecotoxicity.Journal of xenobiotics · 2025Article
- Investigation of antifungal and antibiofilm activities of green synthesized silver nanoparticles against Candida glabrata.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Investigation of adhesion status of Candida species to the surface of resin materials produced at different angles with additive manufacturing.BMC oral health · 2024Article
- Anti-adhesive, anti-biofilm and fungicidal action of newly synthesized gemini quaternary ammonium salts.Scientific reports · 2024Article
- Enhancing the antimicrobial activity of silver nanoparticles against ESKAPE bacteria and emerging fungal pathogens by using tea extracts.Nanoscale advances · 2023Article
- The Antifungal Activities of Syzygium aromaticum and Alpinia purpurata Extracts Against Candida krusei: Bioactivity Tests, Molecular Modeling, and Toxicity Tests.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Anti-biofilm properties of eucalyptol in combination with antifungals against Candida albicans isolates in patients with hematological malignancy.Archives of microbiology · 2022Article
- Natural Compounds for Preventing Ear, Nose, and Throat-Related Oral Infections.Plants (Basel, Switzerland) · 2021Review
- Biomaterials for the Prevention of Oral Candidiasis Development.Pharmaceutics · 2021Review
- Bioactive Coatings with Ag-Camphorimine Complexes to Prevent Surface Colonization by the Pathogenic YeastAntibiotics (Basel, Switzerland) · 2021Article
- Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substrate.Mycopathologia · 2019Article
- Fungal biofilms: From bench to bedside.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2018Review
- Comparative Study of the Effects of Fluconazole and Voriconazole on Candida glabrata, Candida parapsilosis and Candida rugosa Biofilms.Mycopathologia · 2018Article
- Heat-Polymerized Resin Containing Dimethylaminododecyl Methacrylate Inhibits Candida albicans Biofilm.Materials (Basel, Switzerland) · 2017Article
- Biosynthesis of micro- and nanocrystals of Pb (II), Hg (II) and Cd (II) sulfides in four Candida species: a comparative study of in vivo and in vitro approaches.Microbial biotechnology · 2017Article
- Anti-infective Surface Coatings: Design and Therapeutic Promise against Device-Associated Infections.PLoS pathogens · 2016Article
- Influence of culture media on biofilm formation by Candida species and response of sessile cells to antifungals and oxidative stress.BioMed research international · 2015Article
- Screening of Pharmacologically Active Small Molecule Compounds Identifies Antifungal Agents Against Candida Biofilms.Frontiers in microbiology · 2015Article
- Potential Use of Phenolic Acids as Anti-Candida Agents: A Review.Frontiers in microbiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Candida albicans, C. glabrata, C. parapsilosis, and C. tropicalis are able to form biofilms on virtually any biomaterial implanted in a human host. Biofilms are a primary cause of mortality in immunocompromised and hospitalized patients, as they cause recurrent and invasive candidiasis, which is difficult to eradicate. This is due to the fact that the biofilm cells show high resistance to antifungal treatments and the host defense mechanisms, and exhibit an excellent ability to adhere to biomaterials. Elucidation of the mechanisms of antifungal resistance in Candida biofilms is of unquestionable importance; therefore, this review analyzes both the chemical composition of biomaterials used to fabricate the medical devices, as well as the Candida genes and proteins that confer drug resistance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.