SynthesisSurgery today2012
Preoperative carbohydrate loading for elective surgery: a systematic review and meta-analysis.
Synthesis in Surgery today, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05402592 (The Effect of Preoperative Oral Carbohydrate Administration on Postoperative Glucometabolic Response, Subjective Well-being and Quality of Life in Patients Undergoing Colorectal Surgery), which is not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Preoperative Oral Carbohydrate Administration on Postoperative Glucometabolic Response, Subjective Well-being and Quality of Life in Patients Undergoing Colorectal Surgery: A Randomized Prospective Trial
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- Pooled it
- Preoperative carbohydrate treatment for enhancing recovery after elective surgery.The Cochrane database of systematic reviews · 2014Pooled it
- Impact of preoperative carbohydrate loading on gastric volume in patients with type 2 diabetes.World journal of clinical cases · 2022Trial
- SHORTEN PREOPERATIVE FASTING AND INTRODUCING EARLY EATING ASSISTANCE IN RECOVERY AFTER GASTROJEJUNAL BYPASS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022Trial
- Trial
- Article
- Effect of preoperative oral carbohydrate on the postoperative recovery quality of patients undergoing daytime oral surgery: a randomized controlled trial.Perioperative medicine (London, England) · 2024Article
- Evolving Perspectives on Esophagectomy Care: Clinical Update.Anesthesiology · 2023Article
- A review of pediatric fasting guidelines and strategies to help children manage preoperative fasting.Paediatric anaesthesia · 2023Review
- Perioperative carbohydrate loading in patients undergoing one-day surgery. A systematic review of randomized controlled trials.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2022Review
- Attitudes towards Enhanced Recovery after Surgery (ERAS) interventions in colorectal surgery: nationwide survey of Australia and New Zealand colorectal surgeons.Langenbeck's archives of surgery · 2022Article
- Reduced fasting time in patients who underwent totally laparoscopic distal gastrectomy.Annals of surgical treatment and research · 2020Article
- Preoperative patient preparation in enhanced recovery pathways.Journal of anaesthesiology, clinical pharmacology · 2019Review
- Effects of preoperative oral carbohydrate administration on patient well-being and satisfaction in thyroid surgery.Korean journal of anesthesiology · 2018Article
- Enhanced recovery protocols in total joint arthroplasty: a review of the literature and their implementation.Irish journal of medical science · 2018Review
- Paravertebral blocks and enhanced recovery after surgery protocols in breast reconstructive surgery: patient selection and perspectives.Journal of pain research · 2018Review
- Enhanced recovery program is safe and improves postoperative insulin resistance in gastrectomy.World journal of gastrointestinal surgery · 2016Article
- The safety and feasibility of early postoperative oral nutrition on the first postoperative day after gastrectomy for gastric carcinoma.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2014Article
- Preoperative oral rehydration therapy with 2.5 % carbohydrate beverage alleviates insulin action in volunteers.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveIt is unclear whether the preoperative administration of oral carbohydrates (CHO) is safe and effective, and therefore we herein evaluated the efficacy and adverse events associated with CHO for elective surgery.
methodsComprehensive searches were conducted to identify randomized controlled trials (RCTs), which evaluated preoperative CHO for elective surgery. Two reviewers independently selected the trials, extracted data, and assessed the methodological qualities and evidence levels. The data were analyzed by the RevMan 5.0 software program.
resultCHO increased the insulin and glucose levels on the first day after surgery higher than those in overnight fasting group (fifteen RCTs) and i.v. glucose infusion group (three RCTs). The pooled results of thirteen RCTs showed greater declines in the insulin level at the induction of anesthesia and a smaller increase in the glucose level at the end of surgery, and fewer decreases in the postoperative insulin sensitivity index in the CHO group were observed as compared to the placebo group. No aspiration was observed in any of the included studies.
conclusionCHO appears to be safe, and may attenuate postoperative insulin resistance as compared to placebo. However, the quality of most of the published trials has been poor, and the evidence levels for most outcomes were low, so rigorous and larger RCTs are needed in the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.