ArticleEuropean child & adolescent psychiatry2012
How useful are screening instruments for toddlers to predict outcome at age 4? General development, language skills, and symptom severity in children with a false positive screen for autism spectrum disorder.
Article in European child & adolescent psychiatry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Systematic Review and Meta-Analysis of the Clinical Utility of the ADOS-2 and the ADI-R in Diagnosing Autism Spectrum Disorders in Children.Journal of autism and developmental disorders · 2021Pooled it
- Pooled it
- Use of Machine Learning to Investigate the Quantitative Checklist for Autism in Toddlers (Q-CHAT) towards Early Autism Screening.Diagnostics (Basel, Switzerland) · 2021Article
- Detection of Early Warning Signs in Autism Spectrum Disorders: A Systematic Review.Children (Basel, Switzerland) · 2021Review
- Associations between Prenatal Education, Breastfeeding and Autistic-Like Behaviors in Pre-Schoolers.Children (Basel, Switzerland) · 2021Article
- Identification of Symptoms of Autism Spectrum Disorders in the Second Year of Life at Day-Care Centres by Day-Care Staff: Step One in the Development of a Short Observation List.Journal of autism and developmental disorders · 2018Article
- Brief Report: Agreement Between Parents and Day-Care Professionals on Early Symptoms Associated with Autism Spectrum Disorders.Journal of autism and developmental disorders · 2018Article
- Article
- Infant and dyadic assessment in early community-based screening for autism spectrum disorder with the PREAUT grid.PloS one · 2017Article
- Using the PDD Behavior Inventory as a Level 2 Screener: A Classification and Regression Trees Analysis.Journal of autism and developmental disorders · 2016Article
- Severity of Autism Spectrum Disorders: Current Conceptualization, and Transition to DSM-5.Journal of autism and developmental disorders · 2016Article
- Latent class analysis reveals five homogeneous behavioural and developmental profiles in a large Dutch population sample of infants aged 14-15 months.European child & adolescent psychiatry · 2013Article
- Mass spectrometry as a tool for studying autism spectrum disorder.Journal of molecular psychiatry · 2013Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Screening instruments for autism spectrum disorder (ASD) often generate many false positives. It is argued that these children may have other developmental difficulties and are also in need of thorough assessment and early intervention. The current study looked at the predictive validity of positive screens on the Checklist for Early Signs of Developmental Disorders (CESDD) and the Early Screening of Autistic Traits questionnaire (ESAT) at age 2 towards language, cognitive function, and symptom severity at age 4. Children who screened positive on the ESAT scored lower for both language and cognitive functioning at age 4 compared with children who screened negative on the ESAT. Also, the more signs of ASD that were recognized on the CESDD or ESAT, the lower the scores for language and cognitive functioning at age 4. False positive screens could be differentiated from true positive screens on the CESDD only in symptom severity score on the Autism Diagnostic Observation Schedule (ADOS). It seems that early screeners for ASD also detect children with other developmental disorders and that diagnostic instruments such as the ADOS are warranted to differentiate between children with ASD and other developmental problems.
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Registered trials
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