ArticlePlant molecular biology2012
A gain-of-function mutation in IAA16 confers reduced responses to auxin and abscisic acid and impedes plant growth and fertility.
Article in Plant molecular biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed.
- Genome-Wide Analysis of thePlants (Basel, Switzerland) · 2026Article
- Global profiling of alternative splicing landscapes in response to cold stress during the cotyledon stage in cotton.BMC genomics · 2026Article
- The role of auxin-mediated gene activation in the bryophyte, Physcomitrium patens.Journal of experimental botany · 2025Article
- A point mutation in IAA34 confers resistance to the auxin herbicide 2,4-D in Sisymbrium orientale.Pest management science · 2025Article
- The IAA7-ARF7-ARF19 auxin signaling module plays diverse roles in Arabidopsis growth and development.Planta · 2025Article
- The dynamic regulatory network of stamens and pistils in papaya.BMC plant biology · 2025Article
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- Genome-wide identification and expression analysis of ARF gene family in embryonic development of Korean pine (Pinus koraiensis).BMC plant biology · 2024Article
- The chromatin remodeller MdRAD5B enhances drought tolerance by coupling MdLHP1-mediated H3K27me3 in apple.Plant biotechnology journal · 2024Article
- Genome-Wide Analysis of Aux/IAA Gene Family inPlants (Basel, Switzerland) · 2024Article
- Identification of potential auxin response candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.Frontiers in plant science · 2024Article
- A non-canonicalFrontiers in plant science · 2024Article
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- Genetic architecture and genomic prediction of plant height-related traits in chrysanthemum.Horticulture research · 2024Article
- Abscisic acid biosynthesis is necessary for full auxin effects on hypocotyl elongation.Development (Cambridge, England) · 2023Article
- Genome-Wide Characterization of theInternational journal of molecular sciences · 2023Article
- Identification of potential Auxin Response Candidate genes for soybean rapid canopy coverage through comparative evolution and expression analysis.bioRxiv : the preprint server for biology · 2023Article
- Genome-wide identification and expression analysis of the AUX/IAA gene family in turnip (Brassica rapa ssp. rapa).BMC plant biology · 2023Article
- Regulatory Mechanisms ofGenes · 2023Article
- Article
12 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Auxin regulates many aspects of plant development, in part, through degradation of the Aux/IAA family of transcriptional repressors. Consequently, stabilizing mutations in several Aux/IAA proteins confer reduced auxin responsiveness. However, of the 29 apparent Aux/IAA proteins in Arabidopsis thaliana, fewer than half have roles established through mutant analysis. We identified iaa16-1, a dominant gain-of-function mutation in IAA16 (At3g04730), in a novel screen for reduced root responsiveness to abscisic acid. The iaa16-1 mutation also confers dramatically reduced auxin responses in a variety of assays, markedly restricts growth of adult plants, and abolishes fertility when homozygous. We compared iaa16-1 phenotypes with those of dominant mutants defective in the closely related IAA7/AXR2, IAA14/SLR, and IAA17/AXR3, along with the more distantly related IAA28, and found overlapping but distinct patterns of developmental defects. The identification and characterization of iaa16-1 provides a fuller understanding of the IAA7/IAA14/IAA16/IAA17 clade of Aux/IAA proteins and the diverse roles of these repressors in hormone response and plant development.
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