ReviewCurrent psychiatry reports2012
The depression treatment cascade in primary care: a public health perspective.
Review in Current psychiatry reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluating the Efficacy of Telehealth-Based Treatments for Depression in Adults: A Rapid Review and Meta-Analysis.Journal of occupational rehabilitation · 2025Pooled it
- The effectiveness of enhanced evidence-based care for depressive disorders: a meta-analysis of randomized controlled trials.Translational psychiatry · 2021Pooled it
- Disparities in the Treatment Engagement Cascade of Collaborative Care for Depression in a Pragmatic Implementation Study.Psychiatric services (Washington, D.C.) · 2026Trial
- Personalized High-Definition Transcranial Direct Current Stimulation for the Treatment of Depression: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Effect of Computer-Assisted Cognitive Behavior Therapy vs Usual Care on Depression Among Adults in Primary Care: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Predictors of receiving a diagnosis, referral and treatment of depression in people on antiretroviral therapy in South African primary care: a secondary analysis of data from a randomised trial.Tropical medicine & international health : TM & IH · 2020Trial
- Treatment Adequacy and Adherence as Predictors of Depression Response in Primary Care.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Trial
- Efficacy of Three Low-Intensity, Internet-Based Psychological Interventions for the Treatment of Depression in Primary Care: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Personalising psychotherapies for depression using a novel mixed methods approach: an example from Morita therapy.Trials · 2020Trial
- Vilazodone efficacy in subgroups of patients with major depressive disorder: a post-hoc analysis of four randomized, double-blind, placebo-controlled trials.International clinical psychopharmacology · 2018Trial
- Treating major depression with yoga: A prospective, randomized, controlled pilot trial.PloS one · 2017Trial
- A pilot randomized controlled trial of an outreach intervention to improve depression treatment initiation among racial and ethnic groups.General hospital psychiatryTrial
- Team-Effectiveness Barriers and Solutions to Depression Screening within a Pediatric Hospital Network: A Qualitative Study.Evidence-based practice in child and adolescent mental health · 2026Article
- Evaluating mental health integration in PrEP programs to reduce HIV incidence among US gay and bisexual men: a network modeling study.BMC health services research · 2026Article
- The Decision-Making Process of Antidepressant Use Among Patients with Depression: A Grounded Theory Study.Patient preference and adherence · 2026Article
- Evaluating the Real-World Implementation and Effectiveness of a Collaborative Care Model for Adults with Depression and Anxiety at an Urban, Academic Hospital.Journal of evaluation in clinical practice · 2025Article
- Impact of collaborative care model treatment for depression and anxiety on cardiovascular risk factors using electronic health record data.Journal of affective disorders · 2025Article
- Evaluating Clinical Decision Supports to Improve Adolescent Depression Screening and Management in Pediatric Primary Care.Academic pediatrics · 2025Article
- Characteristics Associated with Engagement in the Early Detection Cascade of Care for Psychosis at a College Counseling Center.Community mental health journal · 2025Article
- The effect of antidepressant treatment on viral suppression among people with HIV diagnosed with depression in an urban clinic.AIDS (London, England) · 2025Observational
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Major depressive disorder (MDD) is common and costly. Primary care remains a major access point for depression treatment, yet the successful clinical resolution of depression in primary care is uncommon. The clinical response to depression suffers from a "treatment cascade": the affected individual must access health care, be recognized clinically, initiate treatment, receive adequate treatment, and respond to treatment. Major gaps currently exist in primary care at each step along this treatment continuum. We estimate that 12.5% of primary care patients have had MDD in the past year; of those with MDD, 47% are recognized clinically, 24% receive any treatment, 9% receive adequate treatment, and 6% achieve remission. Simulations suggest that only by targeting multiple steps along the depression treatment continuum (e.g. routine screening combined with collaborative care models to support initiation and maintenance of evidence-based depression treatment) can overall remission rates for primary care patients be substantially improved.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.