Evidence map›Paper›PMID 22580728›Full record

ArticleThe review of diabetic studies : RDS2011

Health care access and prevalence of the metabolic syndrome among elders living in high-altitude areas of the Mediterranean islands: the MEDIS study.

Stefanos Tyrovolas, Christos Chalkias, Marianthi Morena, Ioanna Tsiligianni, Akis Zeimbekis, Efthimios Gotsis, George Metallinos, Vassiliki Bountziouka, Evangelos Polychronopoulos, Christos Lionis and 1 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in The review of diabetic studies : RDS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Cardiometabolic Risk Factors in Women Exposed to High Altitude.International journal of molecular sciences · 2026
    Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Altitudes of residential areas affect salt intake in a rural area in Japan: a Shimane CoHRE Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2015
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Stefanos TyrovolasDepartment of Nutrition and Dietetics, Harokopio University, Athens, Greece.
Christos Chalkias
Marianthi Morena
Ioanna Tsiligianni
Akis Zeimbekis
Efthimios Gotsis
George Metallinos
Vassiliki Bountziouka
Evangelos Polychronopoulos
Christos Lionis
Demosthenes Panagiotakos
Harokopio University of Athens · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of the present work was to evaluate the relationships between sociodemographic, clinical, and lifestyle characteristics and the presence of metabolic syndrome, among high and low altitude living elderly individuals without known CVD.

methodsDuring 2005-2011, 1959 elderly (aged 65 to 100 years) individuals from 13 Mediterranean islands were enrolled. Sociodemographic, clinical, and lifestyle factors were assessed using standard procedures. Metabolic syndrome was defined according to the (Adult Treatment Panel) ATP III criteria. Mountainous areas were defined those more than 400 meters in height.

resultsFor the present analysis 713 men and 596 women were studied; the prevalence of the metabolic syndrome was 29% (24% in men, 35% in women, p < 0.001). Furthermore, the prevalence of metabolic syndrome was 55% in the elders living in mountainous areas, as compared with 26% among those living at sea-level (p = 0.01). Similarly, the prevalence of hypertension, hypercholesterolemia, and obesity were higher in high altitude as compared with low altitude areas (all p-values < 0.01). After adjusting for various confounders, elders living in high altitude areas were 3.06-times more likely to have the metabolic syndrome than those living at sea-level (OR = 3.06, 95%CI 2.02-4.65). However, when the annual number of visits to health care centers was taken into account, the effect of altitude of living was not associated with the presence of the syndrome.

conclusionsA considerable proportion of mountainous living elderly had the metabolic syndrome. Public health actions need to be taken to reduce the burden of cardiometabolic disorders by enabling better access to health care, especially in remote mountainous rural areas.

Indexed as

Health Services AccessibilityRural HealthAgedAged, 80 and overAltitudeCross-Sectional StudiesFemaleHealth Care SurveysHealth SurveysHumansHypercholesterolemiaHypertensionMaleMediterranean IslandsMetabolic SyndromeObesity

Identifiers

PMID22580728
PMCPMC3359691
OpenAlexW336406715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.