Evidence map›Paper›PMID 22580706›Full record

ArticlePlant signaling & behavior2012

CBSXs are sensor relay proteins sensing adenosine-containing ligands in Arabidopsis.

Sung Han Ok, Kyoung Shin Yoo, Jeong Sheop Shin

Open access · bronzeAbstract read
In one paragraph

Article in Plant signaling & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sung Han OkSchool of Life Sciences and Biotechnology, Korea University, Seoul, Korea.
Kyoung Shin Yoo
Jeong Sheop Shin
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently determined that CBSX proteins, which have only one pair of cystathionine β-synthase (CBS) domains, directly regulate the activation of thioredoxins and thereby control cellular H2O2 levels and modulate both plant development and growth. The Arabidopsis genome contains six CBSXs, and these are localized to different subcellular compartments‑ CBSX1 and CBSX2 in the chloroplast, CBSX3 in the mitochondria, CBSX4 in the cytosol, and CBSX5 and CBSX6 in the endoplasmic reticulum. The CBSXs have been identified in prokaryotes and plants, but not in animals. The considerable differences in length and amino acid sequence between CBSX members may result in variations in protein structure and in their specificity to interact with ligands and/or target proteins. Here, we discuss the possibility that the CBSXs are novel sensor relay proteins that use adenosine-containing molecules as a ligand.

Indexed as

Signal TransductionAdenosineArabidopsisArabidopsis ProteinsComputational BiologyLigandsModels, BiologicalAdenosineArabidopsis ProteinsLigands

Identifiers

PMID22580706
PMCPMC3442862
OpenAlexW2083515120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.