Evidence map›Paper›PMID 22579988›Full record

ArticlePhysiology & behavior2012

Leptin concentrations in response to acute stress predict subsequent intake of comfort foods.

A Janet Tomiyama, Imke Schamarek, Robert H Lustig, Clemens Kirschbaum, Eli Puterman, Peter J Havel, Elissa S Epel

Abstract read
In one paragraph

Article in Physiology & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Glucocorticoids, stress and eating: The mediating role of appetite-regulating hormones.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Obesity and Stress: A Contingent Paralysis.International journal of preventive medicine · 2022
    Review
  15. Article
  16. Observational
  17. Review
  18. Review
  19. Article
  20. Overcoming Weight Bias in the Management of Patients With Diabetes and Obesity.Clinical diabetes : a publication of the American Diabetes Association · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

A Janet TomiyamaDepartment of Psychology, UCLA, Los Angeles, CA, USA. tomiyama@psych.ucla.edu
Imke Schamarek
Robert H Lustig
Clemens Kirschbaum
Eli Puterman
Peter J Havel
Elissa S Epel

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Depression, Stress &Health: Role of Anabolic HormonesK08MH064110 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S. · 2002 to 2006
$807k
Chronic and Acute Psychosocial Stress and Impaired Cell AgingR56AG030424 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EPEL, ELISSA S. · 2008 to 2009
$260k
NCRR NIH HHS UL1 RR024131NIA NIH HHS R56 AG030424NIMH NIH HHS K08 MH064110NIMH NIH HHS K08 MH64110-01A1
6 · The paper itself

Abstract

Both animals and humans show a tendency toward eating more "comfort food" (high fat, sweet food) after acute stress. Such stress eating may be contributing to the obesity epidemic, and it is important to understand the underlying psychobiological mechanisms. Prior investigations have studied what makes individuals eat more after stress; this study investigates what might make individuals eat less. Leptin has been shown to increase following a laboratory stressor, and is known to regulate satiety. This study examined whether leptin reactivity accounts for individual differences in stress eating. To test this, we exposed forty women to standardized acute psychological laboratory stress (Trier Social Stress Test) while blood was sampled repeatedly for measurements of plasma leptin. We then measured food intake after the stressor. Increasing leptin during the stressor predicted lower intake of comfort food. These initial findings suggest that acute changes in leptin may be one of the factors modulating down the consumption of comfort food following stress.

Indexed as

FoodAgedAged, 80 and overBody Mass IndexEatingEnergy IntakeFemaleHumansLeptinMiddle AgedPsychological TestsStress, PsychologicalLeptin

Identifiers

PMID22579988
PMCPMC3409346

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.