ArticleJournal of vascular surgery2012
Comparison of carotid endarterectomy and stenting in real world practice using a regional quality improvement registry.
Article in Journal of vascular surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- An umbrella review and second-order meta-analysis of CAS versus CEA for carotid stenosis.Frontiers in neurology · 2026Pooled it
- Combined risk modelling approach to identify the optimal carotid revascularisation approach.Stroke and vascular neurology · 2021Article
- Role of Carotid Artery Stenting in Prevention of Stroke for Asymptomatic Carotid Stenosis: Bayesian Cross-Design and Network Meta-Analyses.Korean circulation journal · 2020Article
- Article
- A comparative analysis of long-term mortality after carotid endarterectomy and carotid stenting.Journal of vascular surgery · 2019Observational
- Comparing Long-term Mortality After Carotid Endarterectomy vs Carotid Stenting Using a Novel Instrumental Variable Method for Risk Adjustment in Observational Time-to-Event Data.JAMA network open · 2018Article
- The impact of race on outcomes after carotid endarterectomy in the United States.Journal of vascular surgery · 2018Article
- The impact of contralateral carotid artery stenosis on outcomes after carotid endarterectomy.Journal of vascular surgery · 2017Article
- Carotid endarterectomy should not be based on consensus statement duplex velocity criteria.Journal of vascular surgery · 2017Article
- Long-term Comparative Outcomes of Carotid Artery Stenting Following Previous Carotid Endarterectomy vs De Novo Lesions.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2015Article
- Clinical relevance of cranial nerve injury following carotid endarterectomy.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2014Article
- The impact of the present on admission indicator on the accuracy of administrative data for carotid endarterectomy and stenting.Journal of vascular surgery · 2014Article
- Carotid stenting versus endarterectomy in patients undergoing reintervention after prior carotid endarterectomy.Journal of vascular surgery · 2014Article
- In-hospital versus postdischarge adverse events following carotid endarterectomy.Journal of vascular surgery · 2013Article
- The effect of postoperative stroke and myocardial infarction on long-term survival after carotid revascularization.Journal of vascular surgery · 2013Article
- The impact of Centers for Medicare and Medicaid Services high-risk criteria on outcome after carotid endarterectomy and carotid artery stenting in the SVS Vascular Registry.Journal of vascular surgery · 2013Article
- Carotid Artery Stenting 2013: Thumbs up.Cardiology research · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveCarotid artery stenting (CAS) vs endarterectomy (CEA) remains controversial and has been the topic of recent randomized controlled trials. The purpose of this study was to compare the practice and outcomes of CAS and CEA in a real world setting.
methodsThis is a retrospective analysis of 7649 CEA and 430 CAS performed at 17 centers from 2003 to 2010 within the Vascular Study Group of New England (VSGNE). The primary outcome measures were (1) any in-hospital stroke or death and (2) any stroke, death, or myocardial infarction (MI). Patients undergoing CEA in conjunction with cardiac surgery were excluded. Multivariate logistic regression was performed to identify predictors of stroke or death in patients undergoing CAS.
resultsCEA was performed in 17 centers by 111 surgeons, while CAS was performed in 6 centers by 30 surgeons and 8 interventionalists. Patient characteristics varied by procedure. Patients undergoing CAS had a higher prevalence of coronary artery disease, congestive heart failure, diabetes, and prior ipsilateral CEA. Embolic protection was used in 97% of CAS. Shunts were used in 48% and patches in 86% of CEA. The overall in-hospital stroke or death rate was higher among patients undergoing CAS (2.3% vs 1.1%; P = .03). Overall stroke, death, or MI (2.8% CAS vs 2.1% CEA; P = .32) were not different. Asymptomatic patients had similar rates of stroke or death (CAS 0.73% vs CEA 0.89%; P = .78) and stroke, death, or MI (CAS 1.1% vs CEA 1.8%; P = .40). Symptomatic patients undergoing CAS had higher rates of stroke or death (5.1% vs 1.6%; P = .001), and stroke, death, or MI (5.8% vs 2.7%; P = .02). By multivariate analysis, major stroke (odds ratio, 4.5; 95% confidence interval [CI], 1.9-10.8), minor stroke (2.7; CI, 1.5-4.8), prior ipsilateral CEA (3.2, CI, 1.7-6.1), age >80 (2.1; CI, 1.3-3.4), hypertension (2.6; CI, 1.0-6.3), and a history of chronic obstructive pulmonary disease (1.6; CI, 1.0-2.4) were predictors of stroke or death in patients undergoing carotid revascularization.
conclusionsIn our regional vascular surgical practices, the overall outcomes of CAS and CEA are similar for asymptomatic patients. However, symptomatic patients treated with CAS are at a higher risk for stroke or death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.