Trial reportJournal of biomechanics2012
Predicting the metabolic cost of incline walking from muscle activity and walking mechanics.
Trial report in Journal of biomechanics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Metabolic Cost of Walking in healthy young and older adults - A Systematic Review and Meta Analysis.Scientific reports · 2019Pooled it
- Effects of visual real-time feedback during decline walking on gait parameters: a crossover randomized trial.BMC musculoskeletal disorders · 2025Trial
- Versatile Exoskeleton Control Supports Elderly Joint Energetics During Hip-Intensive Tasks.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026Article
- Natural variability can increase human walking metabolic costs and its implications to simulation-based metabolic estimation.Journal of the Royal Society, Interface · 2025Article
- A time-efficient continuous ramp protocol for data-driven walking energy expenditure estimation across multiple speeds.Journal of neuroengineering and rehabilitation · 2025Article
- An Exploratory Study Comparing the Metabolic Responses between the 12-3-30 Treadmill Workout and Self-Paced Treadmill Running.International journal of exercise science · 2025Article
- Effects of an active ankle exoskeleton on the walking biomechanics of healthy men.Frontiers in bioengineering and biotechnology · 2025Article
- The effect of incline walking on lower extremity and trunk mechanics in older adults.Sports medicine and health science · 2025Article
- Changes in Dynamic Mean Ankle Moment Arm in Unimpaired Walking Across Speeds, Ramps, and Stairs.Journal of biomechanical engineering · 2024Article
- Article
- Physiological and Psychological Differences Between 20% Grade Incline Walking and Level-Grade Jogging at Isocaloric Intensity.International journal of exercise science · 2024Article
- Muscle coordination and recruitment during squat assistance using a robotic ankle-foot exoskeleton.Scientific reports · 2023Article
- Article
- IMU-Based Classification of Locomotion Modes, Transitions, and Gait Phases with Convolutional Recurrent Neural Networks.Sensors (Basel, Switzerland) · 2022Article
- Humans trade off whole-body energy cost to avoid overburdening muscles while walking.Proceedings. Biological sciences · 2022Article
- Correlation between cardiopulmonary metabolic energy cost and lower-limb muscle activity during inclined treadmill gait in older adults.BMC geriatrics · 2021Article
- Article
- Development and validation of a steep incline and decline metabolic cost equation for steady-state walking.European journal of applied physiology · 2020Article
- Wearable Tendon Kinetics.Sensors (Basel, Switzerland) · 2020Article
- Modular footwear that partially offsets downhill or uphill grades minimizes the metabolic cost of human walking.Royal Society open science · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The goal of this study was to identify which muscle activation patterns and gait features best predict the metabolic cost of inclined walking. We measured muscle activation patterns, joint kinematics and kinetics, and metabolic cost in sixteen subjects during treadmill walking at inclines of 0%, 5%, and 10%. Multivariate regression models were developed to predict the net metabolic cost from selected groups of the measured variables. A linear regression model including incline and the squared integrated electromyographic signals of the soleus and vastus lateralis explained 96% of the variance in metabolic cost, suggesting that the activation patterns of these large muscles have a high predictive value for metabolic cost. A regression model including only the peak knee flexion angle during stance phase, peak knee extension moment, peak ankle plantarflexion moment, and peak hip flexion moment explained 89% of the variance in metabolic cost; this finding indicates that kinematics and kinetics alone can predict metabolic cost during incline walking. The ability of these models to predict metabolic cost from muscle activation patterns and gait features points the way toward future work aimed at predicting metabolic cost when gait is altered by changes in neuromuscular control or the use of an assistive technology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.