Trial reportPsychological medicine2013
Punishment promotes response control deficits in obsessive-compulsive disorder: evidence from a motivational go/no-go task.
Trial report in Psychological medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Prospective relationship between obsessive-compulsive and depressive symptoms during multimodal treatment in pediatric obsessive-compulsive disorder.Child psychiatry and human development · 2014Trial
- Male Sapap3 knockout mice show threat bias under conflict during platform-mediated avoidance task: effects of extinction with response prevention and implications for obsessive compulsive disorder.Translational psychiatry · 2026Article
- Compulsive avoidance in youths and adults with OCD: an aversive pavlovian-to-instrumental transfer study.Translational psychiatry · 2024Article
- Manipulating levels of uncertainty in a decision-making task for obsessive compulsive disorder.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2024Article
- Perseveration and Shifting in Obsessive-Compulsive Disorder as a Function of Uncertainty, Punishment, and Serotonergic Medication.Biological psychiatry global open science · 2024Article
- Executive Functions and Reinforcement Sensitivity in Women with Obsessive Compulsive Symptoms.Iranian journal of psychiatry · 2022Article
- Transdiagnostic phenotypes of compulsive behavior and associations with psychological, cognitive, and neurobiological affective processing.Translational psychiatry · 2022Article
- Association of Environmental Uncertainty With Altered Decision-making and Learning Mechanisms in Youths With Obsessive-Compulsive Disorder.JAMA network open · 2021Article
- Stopping a Response When You Really Care about the Action: Considerations from a Clinical Perspective.Brain sciences · 2021Review
- Dopaminergic drug treatment remediates exaggerated cingulate prediction error responses in obsessive-compulsive disorder.Psychopharmacology · 2019Article
- Free operant observing in humans: a translational approach to compulsive certainty seeking.Quarterly journal of experimental psychology (2006) · 2018Article
- Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders: Cognitive Domains, Neural Circuitry, and Treatment.The international journal of neuropsychopharmacology · 2018Review
- Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2017Article
- Cognitive Dysfunction in Obsessive-Compulsive Disorder.Current psychiatry reports · 2016Review
- Using mice to model Obsessive Compulsive Disorder: From genes to circuits.Neuroscience · 2016Review
- The role of habit in compulsivity.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2016Review
- Divergent subcortical activity for distinct executive functions: stopping and shifting in obsessive compulsive disorder.Psychological medicine · 2016Article
- Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder.Brain : a journal of neurology · 2015Article
- Enhanced avoidance habits in obsessive-compulsive disorder.Biological psychiatry · 2014Article
- The profile of executive function in OCD hoarders and hoarding disorder.Psychiatry research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundObsessive-compulsive disorder (OCD) has been associated with response inhibition deficits under motivationally neutral contingencies. We examined response inhibition performance in the presence of reward and punishment. We further investigated whether the hypothesized difficulties in flexibly updating behaviour based on external feedback in OCD would also lead to a reduced ability to adjust to changes in the reward and punishment contingencies.
methodParticipants completed a go/no-go task that used punishments or rewards to promote response activation or suppression. The task was administered to OCD patients free of current Axis-I co-morbidities including major depression (n = 20) and a group of healthy controls (n = 32).
resultsCompared with controls, patients with OCD had increased commission errors in punishment conditions, and failed to slow down immediately after receiving punishment. The punishment-induced increase in commission errors correlated with self-report measures of OCD symptom severity. Additionally, patients did not differ from controls in adapting their overall response style to the changes in task contingencies.
conclusionsIndividuals with OCD showed reduced response control selectively under punishment conditions, manifesting in an impulsive response style that was related to their current symptom severity. This stresses failures of cognitive control in OCD, particularly under negative motivational contingencies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.