ReviewCurrent opinion in genetics & development2012
Small temporal RNAs in animal development.
Review in Current opinion in genetics & development, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Decoding Argonaute specificity: insights fromRNA (New York, N.Y.) · 2026Review
- A Compilation of the Diverse miRNA Functions inInternational journal of molecular sciences · 2023Review
- Molecular Dissection of a Conserved Cluster of miRNAs Identifies Critical Structural Determinants That Mediate Differential Processing.Frontiers in cell and developmental biology · 2022Article
- miR-335 Restrains the Aggressive Phenotypes of Ovarian Cancer Cells by Inhibiting COL11A1.Cancers · 2021Article
- LentiRILES, a miRNA-ON sensor system for monitoring the functionality of miRNA in cancer biology and therapy.RNA biology · 2021Article
- Expression profiling of Echinococcus multilocularis miRNAs throughout metacestode development in vitro.PLoS neglected tropical diseases · 2021Article
- Article
- Dynamic Changes in the Global Transcriptome and MicroRNAome Reveal Complex miRNA-mRNA Regulation in Early Stages of the Bi-Directional Development ofFrontiers in microbiology · 2020Article
- MicroRNA-204-5p Inhibits Ovarian Cancer Cell Proliferation by Down-Regulating USP47.Cell transplantation · 2019Article
- MicroRNA in Ovarian Cancer: Biology, Pathogenesis, and Therapeutic Opportunities.International journal of environmental research and public health · 2019Review
- Celebrating 25 Years of MicroRNA Research: From Discovery to Clinical Application.International journal of molecular sciences · 2019Article
- Dysregulation of Neuronal Gαo Signaling by Graphene Oxide in Nematode Caenorhabditis elegans.Scientific reports · 2019Article
- The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system.The Journal of biological chemistry · 2019Article
- Effects of let-7c on the proliferation of ovarian carcinoma cells by targeted regulation of CDC25a gene expression.Oncology letters · 2018Article
- Elucidating the Small Regulatory RNA Repertoire of the Sea Anemone Anemonia viridis Based on Whole Genome and Small RNA Sequencing.Genome biology and evolution · 2018Article
- Expression of microRNAs in tumors of the central nervous system in pediatric patients in México.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Multi-walled carbon nanotubes-induced alterations in microRNA let-7 and its targets activate a protection mechanism by conferring a developmental timing control.Particle and fibre toxicology · 2017Article
- 11q deletion in neuroblastoma: a review of biological and clinical implications.Molecular cancer · 2017Review
- Molecular Control of Innate Immune Response to Pseudomonas aeruginosa Infection by Intestinal let-7 in Caenorhabditis elegans.PLoS pathogens · 2017Article
- A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila.PLoS genetics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The lin-4/miR-125 and let-7 microRNAs are at the heart of the heterochronic pathway, which controls temporal cell fate determination during Caenorhabditis elegans development. These small temporal RNAs are clustered along with a third microRNA, miR-100, in the genomes of most animals. Their conserved temporal and neural expression profile suggests a general role in cell fate determination during nervous system differentiation. By triggering consecutive differentiation programs, these microRNAs probably help to determine birth-order dependent temporal identity and thereby contribute to neural stem cell multipotency.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.