Evidence map›Paper›PMID 22577982›Full record

ArticleCritical care (London, England)2012

Micronutrients against oxidative stress--time for clinical recommendations?

Jan Wernerman

Abstract readComment
In one paragraph

Article in Critical care (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Jan Wernerman

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant micronutrient supplementation may be beneficial for critically ill patients. Often, cocktails of antioxidant micronutrients are used. Consequently, meta-analyses of available randomized controlled trials of antioxidant micronutrient supplementation are of particular interest. Because the majority of randomized controlled trials included in these meta-analyses use a combination of several antioxidant micronutrients, conclusions are difficult to draw. The scientific step to take now is to gain more knowledge about antioxidant mechanisms by coupling plasma concentrations to effects and outcomes.

Indexed as

Dietary SupplementsHospital MortalityCritical IllnessHumansMicronutrientsMicronutrients

Identifiers

PMID22577982
PMCPMC3580608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.