Evidence map›Paper›PMID 22577476›Full record

ArticleDeutsches Arzteblatt international2012

Atrial fibrillation: its prevalence and risk factor profile in the German general population.

Renate B Schnabel, Sandra Wilde, Philipp S Wild, Thomas Munzel, Stefan Blankenberg

2 registry-linked trialsAbstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03004859 completednot on this mapstarted 2017, after this paper: background citation

Eine Beobachtungsstudie Zur Erfassung Von (Asymptomatischem)Vorhofflimmern Mittels Eines Gelegenheitsscreenings älteren Menschen ab 65 Jahren

Typeobservational_patient_registrySponsorRWTH Aachen UniversityRan2017 to 2018Enrolled7,606ConditionsIncidence of Atrial Fibrillation in Adults Aged ≥ 65
NCT03715361 completednot on this mapstarted 2018, after this paper: background citation

AF Stroke Substudy SL-ECG Versus 12lead ECG

TypeobservationalSponsorRWTH Aachen UniversityRan2018 to 2019Enrolled550ConditionsECG, Atrial Fibrillation, ECG Hand-held Diagnostic ToolArmsSL-ECG
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. The Value of Left Atrial Strain and Strain Rate for Prediction of Early Postoperative Atrial Fibrillation Following Isolated Off-Pump Coronary Artery Bypass Grafting in Low-Risk Patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
  6. Critique on the Fibrillatory Wave Amplitude of ECG Decreases Over Time in Patients With Persistent AF.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. [What is confirmed in the treatment of atrial fibrillation?]Innere Medizin (Heidelberg, Germany) · 2022
    Review
  15. Article
  16. Lower levels of vWF are associated with lower risk of cardiovascular disease.Research and practice in thrombosis and haemostasis · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Renate B SchnabelDepartment of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Hamburg, Germany. schnabelr@gmx.de
Sandra Wilde
Philipp S Wild
Thomas Munzel
Stefan Blankenberg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is an increasingly common problem in primary care, but little is known about its prevalence and the distribution of AF risk factors in the general population.

methodsWe determined the prevalence of AF and the distribution of known AF risk factors among persons participating in the population-based Gutenberg Health Study. To this end, we used interview data about the medical diagnosis of AF and electrocardiograms (ECGs) that were performed for the study in 5000 persons aged 35 to 74. The response rate was 60.4%.

resultsThere were 5000 persons in the study sample (age 52.2 ± 11 years; 50.6% were women). The prevalence of AF, weighted for the age and sex distribution of the general population, was 2.5%. AF was found to be more common in older persons, with a more pronounced increase in men: whereas its prevalence was 0.7% in 35- to 44-year-old men, the corresponding figure for the age group 65- to 74 was as high as 10.6%. Twenty five participants (15.5% of AF cases) received their initial diagnosis of AF on the basis of the study ECG. Compared to persons without AF, persons with AF were older and more commonly male, and they had a higher burden of cardiovascular risk factors. 14.3% of persons with AF had none of the well-established risk factors for AF (systolic blood pressure, antihypertensive medication, increased body-mass-index, heart failure). 42.7% of persons with AF were not taking either anticoagulants or platelet inhibitors.

conclusionThese data indicate that the prevalence of AF in the middle-aged general population is 2.5% overall, and higher in the elderly. AF is thus a significant public health problem, and greater awareness of it is needed.

Indexed as

AdultAgedAge DistributionAtrial FibrillationComorbidityFemaleGermanyHumansMaleMiddle AgedPrevalenceRisk AssessmentRisk FactorsSex DistributionStrokeSurvival Analysis

Identifiers

PMID22577476
PMCPMC3349225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.