Evidence map›Paper›PMID 22577366›Full record

ArticleInternational journal of biomedical imaging2012

A review of indocyanine green fluorescent imaging in surgery.

Jarmo T Alander, Ilkka Kaartinen, Aki Laakso, Tommi Pätilä, Thomas Spillmann, Valery V Tuchin, Maarit Venermo, Petri Välisuo

8 registry-linked trialsAbstract read
In one paragraph

Article in International journal of biomedical imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 566 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
566citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03587532 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Assessment of Graft Perfusion and Oxygenation for Improved Outcome in Esophageal Cancer Surgery

TypeinterventionalSponsorUniversity Hospital, GhentRan2021 to 2024Enrolled70ConditionsAnastomotic Leak, Esophageal CancerArmsIndocyanine green angiography, Hemodynamic evaluation, Biological and pathological markers of ischemia
NCT03860493 completednot on this mapstarted 2019, after this paper: background citation

Feasibility of the IC-Flow Device for Fluorescent Perfusion Evaluation During Open Surgical Procedures

TypeobservationalSponsorThe Cleveland ClinicRan2019 to 2020Enrolled6ConditionsSkin Flap Necrosis, Perfusion, ComplicationsArmsPerfusion evaluation with indocyanine green
NCT04107623 nacompletednot on this mapstarted 2020, after this paper: background citation

Quantitative Fluorescent Guided Robotic Surgery for Cancer of the Gastroesophageal Junction

TypeinterventionalSponsorRigshospitalet, DenmarkRan2020 to 2021Enrolled70ConditionsStomach Neoplasms, SurgeryArmsIndocyanine Green
NCT04904081 phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

The Use of Indocyanine Green Angiography in Pediatric Colorectal Surgery: A Feasibility Randomized Controlled Trial

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2021 to 2024Enrolled12ConditionsHirschsprung Disease, Anorectal MalformationsArmsIndocyanine green
NCT04908826 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Comparison of Administration of Indocyanine Green (ICG) for Image-Guided Laparoscopic Cholocystectomy- A Randomized, Controlled, Prospective Trial

TypeinterventionalSponsorAristotle University Of ThessalonikiRan2022 to 2023Enrolled240ConditionsLaparoscopic, Cholecystectomy, Cholelithiasis, Bile DuctArmsIndocyanine Green (ICG) administration
NCT05072717 nawithdrawnnot on this mapstarted 2022, after this paper: background citation

Single-center Pilot Prospective Observational Study to Determine Feasibility of Assessing Meniscal Tissue Vascularity Using Dynamic Contrast-enhanced Fluorescence Arthroscopy

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2022 to 2023Enrolled0ConditionsKnee InjuriesArmsPerfusion with Indocyanine green
NCT05117853 phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

The Use of Autofluorescence and Indocyanine Green to Avoid Hypocalcemia After Total Thyroidectomy: A Randomized Clinical Trial

TypeinterventionalSponsorOnze Lieve Vrouw HospitalRan2021 to 2025Enrolled300ConditionsThyroid Disease, Hypoparathyroidism PostproceduralArmsAutofluorescent detection + Injection of indocyanine green, Gold standard of visual identification and evaluation of viability of the parathyroid glands.
NCT05354856 phase4terminatednot on this mapstarted 2022, after this paper: background citation

The Effect of Chemoradiotherapy on Gastric Perfusion in Patients With Gastric Cancer.

TypeinterventionalSponsorRigshospitalet, DenmarkRan2022 to 2023Enrolled11ConditionsGastric CancerArmsIndocyanine green
3 · Its place in the literature

Who cites it

566 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  9. Guideline
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  11. Trial
  12. Phase 2 Dose-Ranging Trial of VGT-309 for Molecular Imaging of Cancer during Pulmonary Resection.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
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  17. Review
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  20. Observational

506 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jarmo T AlanderDepartment of Electrical Engineering and Energy Technology, University of Vaasa, Vaasa, Finland.
Ilkka Kaartinen
Aki Laakso
Tommi Pätilä
Thomas Spillmann
Valery V Tuchin
Maarit Venermo
Petri Välisuo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this paper is to give an overview of the recent surgical intraoperational applications of indocyanine green fluorescence imaging methods, the basics of the technology, and instrumentation used. Well over 200 papers describing this technique in clinical setting are reviewed. In addition to the surgical applications, other recent medical applications of ICG are briefly examined.

Identifiers

PMID22577366
PMCPMC3346977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.