ArticleMediators of inflammation2012
Cytokines in pericardial effusion of patients with inflammatory pericardial disease.
Article in Mediators of inflammation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Compartmentalization of the Inflammatory Response in the Pericardial Cavity in Patients Undergoing Cardiac Surgery.International journal of molecular sciences · 2024Article
- National Estimates for the Percentage of All Readmissions With Demographic Features, Morbidity, Overall and Gender-Specific Mortality of Transcutaneous Versus Open Surgical Tricuspid Valve Replacement/Repair.Cardiology research · 2024Review
- Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers.Frontiers in oncology · 2024Article
- Accumulation of Inflammatory Mediators in the Normal Pericardial Fluid.International journal of molecular sciences · 2023Article
- MicroRNAs (miRNAs) in Cardiovascular Complications of Rheumatoid Arthritis (RA): What Is New?International journal of molecular sciences · 2022Review
- Occurrence and predictors of pericardial effusion requiring invasive treatment following heart valve surgery.Open heart · 2022Observational
- A bioinformatics approach for identifying potential molecular mechanisms and key genes involved in COVID-19 associated cardiac remodeling.Gene reports · 2021Article
- The Multifunctional Contribution of FGF Signaling to Cardiac Development, Homeostasis, Disease and Repair.Frontiers in cell and developmental biology · 2021Review
- The incidence of myopericarditis in patients with COVID-19.Journal of cardiovascular and thoracic research · 2021Article
- An unusual interventricular septal bounce in a patient with dermatomyositis: a case report.European heart journal. Case reports · 2019Article
- Acute Influenza Infection Presenting with Cardiac Tamponade: A Case Report and Review of Literature.The Permanente journal · 2019Article
- Established and novel pathophysiological mechanisms of pericardial injury and constrictive pericarditis.World journal of cardiology · 2018Review
- Calcitriol downregulates fibroblast growth factor receptor 1 through histone deacetylase activation in HL-1 atrial myocytes.Journal of biomedical science · 2018Article
- Influenza H1N1 Infection Leading To Cardiac Tamponade in a Previously Healthy Patient: A Case Report.Research in cardiovascular medicine · 2016Article
- Roles of FGF Signals in Heart Development, Health, and Disease.Frontiers in cell and developmental biology · 2016Review
- Diacetyloxyl derivatization of the fibroblast growth factor inhibitor dobesilate enhances its anti-inflammatory, anti-angiogenic and anti-tumoral activities.Journal of translational medicine · 2015Article
- Article
- Dramatic response to inhaled dobesilate in a patient with lung squamous cell cancer.BMJ case reports · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe role of inflammatory and angiogenic cytokines in patients with inflammatory pericardial effusion still remains uncertain.
methodsWe assessed pericardial and serum levels of VEGF, bFGF, IL-1β and TNF-α by ELISA in patients with inflammatory pericardial effusion (PE) of autoreactive (n = 22) and viral (n = 11) origin, and for control in pericardial fluid (PF) and serum (n = 26) of patients with coronary artery disease (CAD) undergoing coronary artery bypass graft surgery.
resultsVEGF levels were significantly higher in patients with autoreactive and viral PE than in patients with CAD in both PE (P = 0.006 for autoreactive and P < 0.001 for viral PE) and serum (P < 0.001 for autoreactive and P < 0.001 for viral PE). Pericardial bFGF levels were higher compared to serum levels in patients with inflammatory PE and patients with CAD (P ≤ 0.001 for CAD; P ≤ 0.001 for autoreactive PE; P = 0, 005 for viral PE). Pericardial VEGF levels correlated positively with markers of pericardial inflammation, whereas pericardial bFGF levels showed a negative correlation. IL-1β and TNF-α were detectable only in few PE and serum samples.
conclusionsVEGF and bFGF levels in pericardial effusion are elevated in patients with inflammatory PE. It is thus possible that VEGF and bFGF participate in the pathogenesis of inflammatory pericardial disease.
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