ArticleThe Journal of biological chemistry2012
Light-dependent, dark-promoted interaction between Arabidopsis cryptochrome 1 and phytochrome B proteins.
Article in The Journal of biological chemistry, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- The Photoreceptors Phototropin 1 and Phytochrome B Mediate Moonlight Perception and Response inPlants (Basel, Switzerland) · 2026Article
- The photolyase/cryptochrome of Aspergillus nidulans senses oxidative stress and shuttles from nuclei to mitochondria.Nature communications · 2026Article
- Cryptochrome 1 in the dark affects phytochrome A in etiolated Arabidopsis seedlings shifting the balance between its native types, phyA' and phyA″.Protoplasma · 2025Article
- Diurnal Rhythms in the Red Seaweed Gracilariopsis chorda are Characterized by Unique Regulatory Networks of Carbon Metabolism.Molecular biology and evolution · 2024Article
- Magic Blue Light: A Versatile Mediator of Plant Elongation.Plants (Basel, Switzerland) · 2023Review
- PIF7 is a master regulator of thermomorphogenesis in shade.Nature communications · 2022Article
- Coordinated regulation of plant immunity by poly(ADP-ribosyl)ation and K63-linked ubiquitination.Molecular plant · 2021Article
- Optobiochemistry: Genetically Encoded Control of Protein Activity by Light.Annual review of biochemistry · 2021Review
- A LexA-based yeast two-hybrid system for studying light-switchable interactions of phytochromes with their interacting partners.aBIOTECH · 2021Article
- Cryptochromes integrate green light signals into the circadian system.Plant, cell & environment · 2020Article
- Rapid Examination of Phytochrome-Phytochrome Interacting Factor (PIF) Interaction by In Vitro Coimmunoprecipitation Assay.Methods in molecular biology (Clifton, N.J.) · 2019Article
- Transcriptomic analyses of cacao cell suspensions in light and dark provide target genes for controlled flavonoid production.Scientific reports · 2018Article
- New insights into the mechanisms of phytochrome-cryptochrome coaction.The New phytologist · 2018Review
- Green-Light-Induced Inactivation of Receptor Signaling Using Cobalamin-Binding Domains.Angewandte Chemie (International ed. in English) · 2017Article
- Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci.Developmental cell · 2015Article
- Shade avoidance components and pathways in adult plants revealed by phenotypic profiling.PLoS genetics · 2015Article
- Proton transfer to flavin stabilizes the signaling state of the blue light receptor plant cryptochrome.The Journal of biological chemistry · 2015Article
- Applications of hydrogen deuterium exchange (HDX) for the characterization of conformational dynamics in light-activated photoreceptors.Frontiers in molecular biosciences · 2015Review
- Illuminating cell signalling with optogenetic tools.Nature reviews. Molecular cell biology · 2014Review
- Optogenetic control of cell function using engineered photoreceptors.Biology of the cell · 2013Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Plant photoreceptors transduce environmental light cues to downstream signaling pathways, regulating a wide array of processes during growth and development. Two major plant photoreceptors with critical roles in photomorphogenesis are phytochrome B (phyB), a red/far-red absorbing photoreceptor, and cryptochrome 1 (CRY1), a UV-A/blue photoreceptor. Despite substantial genetic evidence for cross-talk between phyB and CRY1 pathways, a direct interaction between these proteins has not been observed. Here, we report that Arabidopsis phyB interacts directly with CRY1 in a light-dependent interaction. Surprisingly, the interaction is light-dissociated; CRY1 interacts specifically with the dark/far-red (Pr) state of phyB, but not with the red light-activated (Pfr) or the chromophore unconjugated form of the enzyme. The interaction is also regulated by light activation of CRY1; phyB Pr interacts only with the unstimulated form of CRY1 but not with the photostimulated protein. Further studies reveal that a small domain extending from the photolyase homology region (PHR) of CRY1 regulates the specificity of the interaction with different conformational states of phyB. We hypothesize that in plants, the phyB/CRY1 interaction may mediate cross-talk between the red/far-red- and blue/UV-sensing pathways, enabling fine-tuning of light responses to different spectral inputs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.