ArticleEuropean journal of nuclear medicine and molecular imaging2012
Parametric imaging of myocardial viability using ¹⁵O-labelled water and PET/CT: comparison with late gadolinium-enhanced CMR.
Article in European journal of nuclear medicine and molecular imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Trajectories and determinants of echocardiographic myocardial work indices after acute myocardial infarction: a pilot study.Echo research and practice · 2026Article
- Improvement in the estimation of perfusable tissue fraction and myocardial flow reserve in the ischemic myocardial lesions using ECG-gated dynamic myocardial PET withAnnals of nuclear medicine · 2024Article
- Influence of image reconstruction on quantitative cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Assessment of myocardial viability with [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia.Nature reviews. Cardiology · 2020Article
- In vivo assessment of myocardial viability after acute myocardial infarction: A head-to-head comparison of the perfusable tissue index by PET and delayed contrast-enhanced CMR.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Myocardial denervation coincides with scar heterogeneity in ischemic cardiomyopathy: A PET and CMR study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- F-18 fluorodeoxyglucose uptake and water-perfusable tissue fraction in assessment of myocardial viability.Annals of nuclear medicine · 2012Article
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Authors and funding
11 authors.
Funding
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Abstract
purposeThe perfusable tissue index (PTI) is a marker of myocardial viability. Recent technological advances have made it possible to generate parametric PTI images from a single [(15)O]H(2)O PET/CT scan. The purpose of this study was to validate these parametric PTI images.
methodsThe study population comprised 46 patients with documented or suspected coronary artery disease who were studied with [(15)O]H(2)O PET and late gadolinium-enhanced (LGE) cardiac magnetic resonance imaging (CMR).
resultsOf the 736 myocardial segments included, 364 showed some degree of LGE. PTI and perfusable tissue fraction (PTF) diminished with increasing LGE. The areas under the curve of the PTI and PTF, used to predict (near) transmural LGE on CMR, were 0.86 and 0.87, respectively. Optimal sensitivity and specificity were 91 % and 73 % for PTI and 69 % and 87 % for PTF, respectively.
conclusionPTI and PTF assessed with a single [(15)O]H(2)O scan can be utilized as markers of myocardial viability in patients with coronary artery disease.
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