ArticleParasitology research2012
Cassia alata L: potential role as anthelmintic agent against Hymenolepis diminuta.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Preclinical evaluation of Senna alata leaf extract against Hymenolepis diminuta: a promising natural anthelmintic solution.BMC complementary medicine and therapies · 2026Article
- Prevalence of intestinal parasites in laboratory rats and mice and effectiveness of aqueous extracts from carob pods, Moringa oleifera, and Artemisia alba on the zoonotic parasite Hymenolepis diminuta infection.Acta parasitologica · 2025Article
- Exploring Metabolic Disruption and Redox Modulation by Senna Leaf Extracts Induces Mortality in the Zoonotic ParasiteJournal of parasitology research · 2025Article
- Anthelmintic Activity ofCombinatorial chemistry & high throughput screening · 2025Article
- Article
- In vitro anthelmintic efficacy of Ferulic and Sinapic acid against zoonotic cestodeJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- Anthelmintic evaluation of three ayurvedic formulations: a transmission electron microscopy study inJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023Article
- Gallic acid and Catechin induce morphological alterations on the zoonotic parasite Hymenolepis diminuta.Parasitology research · 2023Article
- The complete chloroplast genome ofMitochondrial DNA. Part B, Resources · 2023Article
- The TapewormPathogens (Basel, Switzerland) · 2022Review
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- Effect ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov.Molecules (Basel, Switzerland) · 2021Review
- Review
- Ethnobotanical Description and Biological Activities ofEvidence-based complementary and alternative medicine : eCAM · 2020Review
- In vitro efficacy of latex and purified papain from Carica papaya against Strongyloides venezuelensis eggs and larvae.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Article
- Article
- Anthelmintic effects of Oroxylum indicum stem bark extract on juvenile and adult stages of Hymenolepis diminuta (Cestoda), an in vitro and in vivo study.Parasitology research · 2016Article
- Broad spectrum anthelmintic potential of Cassia plants.Asian Pacific journal of tropical biomedicine · 2014Article
- Anthelmintic activities of aporphine from Nelumbo nucifera Gaertn. cv. Rosa-plena against Hymenolepis nana.International journal of molecular sciences · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of Cassia alata against cestode Hymenolepis diminuta was evaluated in our study. Worms were maintained between rat model and beetle. Air-dried leaves of C. alata were subjected to ethanol extraction. Different concentrations (10-80 mg/ml) of the extract were prepared in phosphate buffer saline and tested on the parasite in vitro. Parasites treated with C. alata showed a decrease in motility with an increase in concentrations and complete immobilization took lesser time compared to control. The paralyzed parasites were further processed for electron microscopic studies. Ultrastructural micrographs revealed swelling of the tegument and blebbing on the tegumental surface throughout the body accompanied with destruction of microtriches and changes such as shrinkage in the scolex region. Depletion of parenchyma cells and destruction in the connective tissues along with sparsely cytoplasmic cytons were also observed, and these observations are similar with worms treated with a known drug praziquantel. These results may suggest that the plant leaves could be considered for controlling helminth infection and can represent a step forward in the search for alternative anthelmintic drug.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.