ReviewVirchows Archiv : an international journal of pathology2012
Macrophage-related diseases of the gut: a pathologist's perspective.
Review in Virchows Archiv : an international journal of pathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Malakoplakia of the small intestine presenting as an abdominal mass.Journal of surgical case reports · 2023Article
- A Surgical Challenge Generated by Colonic Malakoplakia in Disguise as a Locally Advanced Colonic Malignancy-A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Whipple's Disease with Colonic Involvement: A Rare Endoscopic Documentation.GE Portuguese journal of gastroenterology · 2022Article
- Identification of CX3CR1iScience · 2022Article
- Acid Sphingomyelinase Deficiency: A Clinical and Immunological Perspective.International journal of molecular sciences · 2021Review
- Malakoplakia mimicking a locally advanced colorectal neoplasm.Journal of surgical case reports · 2021Article
- Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions.Scientific reports · 2017Article
- Whipple's disease in granulomatous disguise: a challenging diagnosis with many histopathological pitfalls.Virchows Archiv : an international journal of pathology · 2017Article
- Two Cases of Rectal Xanthoma Presenting as Yellowish to Whitish Lesions during Colonoscopy.Case reports in gastrointestinal medicine · 2017Article
- Social stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri.Mucosal immunology · 2016Article
- Neuroimmunomodulation in the Gut: Focus on Inflammatory Bowel Disease.Mediators of inflammation · 2016Review
- Colonic Carcinoma Associated with Malakoplakia.The West Indian medical journal · 2014Article
- Apigenin induces the apoptosis and regulates MAPK signaling pathways in mouse macrophage ANA-1 cells.PloS one · 2014Article
- Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection.BMC genomics · 2013Article
- Whipple's Disease: Our Own Experience and Review of the Literature.Gastroenterology research and practice · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The resident macrophages of the gastrointestinal tract represent the largest population of macrophages in the human body and are usually located in the subepithelial lamina propria. This strategic location guarantees a first-line defense to the huge numbers of potentially harmful bacteria and antigenic stimuli that are present in the intestinal lumen. In non-inflamed mucosa, macrophages phagocytose and kill microbes in the absence of an inflammatory response. However, in the event of an epithelial breach and/or microbial invasion, new circulating monocytes and lymphocytes will be recruited to the damaged area of the gut, which will result in the secretion of proinflammatory mediators and engage a protective inflammatory response. Although macrophages are usually not conspicuous in normal mucosal samples of the gut, they can easily be detected when they accumulate exogenous particulate material or endogenous substances or when they become very numerous. These events will mostly occur in pathologic conditions, and this review presents an overview of the diseases which are either mediated by or affecting the resident macrophages of the gut.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.